Pinophilin B

Details

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Internal ID 3ce36a3b-07ed-4be2-a844-ff5026d542c6
Taxonomy Benzenoids > Benzene and substituted derivatives > Benzoic acids and derivatives > p-Hydroxybenzoic acid esters > p-Hydroxybenzoic acid alkyl esters
IUPAC Name [(7S,8S,8aS)-7-hydroxy-3-[(E)-3-hydroxyprop-1-enyl]-7-methyl-6-oxo-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoate
SMILES (Canonical) CC1=CC(=CC(=C1C(=O)OC2C3COC(=CC3=CC(=O)C2(C)O)C=CCO)O)O
SMILES (Isomeric) CC1=CC(=CC(=C1C(=O)O[C@H]2[C@@H]3COC(=CC3=CC(=O)[C@@]2(C)O)/C=C/CO)O)O
InChI InChI=1S/C21H22O8/c1-11-6-13(23)9-16(24)18(11)20(26)29-19-15-10-28-14(4-3-5-22)7-12(15)8-17(25)21(19,2)27/h3-4,6-9,15,19,22-24,27H,5,10H2,1-2H3/b4-3+/t15-,19+,21-/m1/s1
InChI Key KKSKNERURMTALE-XWEVTOJWSA-N
Popularity 5 references in papers

Physical and Chemical Properties

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Molecular Formula C21H22O8
Molecular Weight 402.40 g/mol
Exact Mass 402.13146766 g/mol
Topological Polar Surface Area (TPSA) 134.00 Ų
XlogP 1.30

Synonyms

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((7S,8S,8aS)-7-hydroxy-3-((E)-3-hydroxyprop-1-enyl)-7-methyl-6-oxo-8,8a-dihydro-1H-isochromen-8-yl) 2,4-dihydroxy-6-methylbenzoate
[(7S,8S,8aS)-7-hydroxy-3-[(E)-3-hydroxyprop-1-enyl]-7-methyl-6-oxo-8,8a-dihydro-1H-isochromen-8-yl] 2,4-dihydroxy-6-methylbenzoate
RefChem:174354
1355612-70-2
CHEMBL2011647
CHEBI:202740
BDBM50379294

2D Structure

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2D Structure of Pinophilin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.41% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.85% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.91% 89.00%
CHEMBL1929 P47989 Xanthine dehydrogenase 92.14% 96.12%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.98% 95.56%
CHEMBL340 P08684 Cytochrome P450 3A4 91.37% 91.19%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.86% 86.33%
CHEMBL2581 P07339 Cathepsin D 90.41% 98.95%
CHEMBL1994 P08235 Mineralocorticoid receptor 89.72% 100.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.14% 96.09%
CHEMBL4208 P20618 Proteasome component C5 86.28% 90.00%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 85.86% 93.40%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 84.78% 96.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.37% 99.17%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.92% 99.23%
CHEMBL3401 O75469 Pregnane X receptor 83.25% 94.73%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.77% 97.09%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 81.67% 94.80%
CHEMBL1937 Q92769 Histone deacetylase 2 81.31% 94.75%
CHEMBL3194 P02766 Transthyretin 80.93% 90.71%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.83% 91.07%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.69% 82.38%
CHEMBL279 P35968 Vascular endothelial growth factor receptor 2 80.55% 95.52%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 80.50% 90.93%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 80.05% 91.24%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 57333718
LOTUS LTS0205598
wikiData Q77373253