Phyllactone A

Details

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Internal ID 05a226d1-f873-42f1-ad49-ef59f9009188
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Sesterterpenoids > Scalarane sesterterpenoids
IUPAC Name [(3R,4R,5aS,5bR,7aS,8S,11aS,11bR,13R,13aS)-8-ethyl-4-hydroxy-3,5b,8,11a,13a-pentamethyl-1-oxo-4,5,5a,6,7,7a,9,10,11,11b,12,13-dodecahydro-3H-phenanthro[2,1-e][2]benzofuran-13-yl] 3-hydroxypentanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H50O6/c1-8-19(33)15-25(35)38-24-17-22-30(5)13-10-12-29(4,9-2)21(30)11-14-31(22,6)23-16-20(34)26-18(3)37-28(36)27(26)32(23,24)7/h18-24,33-34H,8-17H2,1-7H3/t18-,19?,20-,21+,22-,23+,24-,29+,30+,31-,32-/m1/s1
InChI Key ASNLHWDCHRXQBN-CSYAWAKVSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C32H50O6
Molecular Weight 530.70 g/mol
Exact Mass 530.36073931 g/mol
Topological Polar Surface Area (TPSA) 93.10 Ų
XlogP 6.40

Synonyms

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Phyllactone B
145613-54-3
D(17a)-Homopregn-17-ene-17a-carboxylic acid, 4-ethyl-16,20-dihydroxy-12-((3-hydroxy-1-oxopentyl)oxy)-4,8-dimethyl-, gamma-lactone, (4beta,5alpha,12beta,16alpha,20R)-
CHEMBL450249
DTXSID60932656
[(3R,4R,5aS,5bR,7aS,8S,11aS,11bR,13R,13aS)-8-ethyl-4-hydroxy-3,5b,8,11a,13a-pentamethyl-1-oxo-4,5,5a,6,7,7a,9,10,11,11b,12,13-dodecahydro-3H-phenanthro[2,1-e][2]benzofuran-13-yl] 3-hydroxypentanoate
8-Ethyl-4-hydroxy-3,5b,8,11a,13a-pentamethyl-1-oxo-1,3,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydrochryseno[1,2-c]furan-13-yl 3-hydroxypentanoate

2D Structure

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2D Structure of Phyllactone A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.41% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.66% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.42% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.36% 97.09%
CHEMBL2581 P07339 Cathepsin D 92.61% 98.95%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 91.48% 82.69%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.84% 95.56%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 90.47% 96.38%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.75% 89.00%
CHEMBL237 P41145 Kappa opioid receptor 88.30% 98.10%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 87.87% 92.62%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 87.53% 97.14%
CHEMBL5103 Q969S8 Histone deacetylase 10 85.45% 90.08%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 84.90% 91.07%
CHEMBL299 P17252 Protein kinase C alpha 83.83% 98.03%
CHEMBL340 P08684 Cytochrome P450 3A4 83.02% 91.19%
CHEMBL2096618 P11274 Bcr/Abl fusion protein 82.95% 85.83%
CHEMBL221 P23219 Cyclooxygenase-1 82.92% 90.17%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.54% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.96% 86.33%
CHEMBL218 P21554 Cannabinoid CB1 receptor 81.52% 96.61%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 80.86% 98.75%
CHEMBL5028 O14672 ADAM10 80.58% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 3081879
LOTUS LTS0080344
wikiData Q82908375