Phomopchalasin B

Details

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Internal ID e6a2f665-4f44-458f-be88-274188a235fd
Taxonomy Organoheterocyclic compounds > Isoindoles and derivatives
IUPAC Name (1S,3S,4R,5S,8R,9S,10R,11R,14S,16R,18R)-5-benzyl-9,10-dihydroxy-3,12,14-trimethyl-2-methylidene-19-oxa-6-azapentacyclo[14.2.1.04,8.08,18.011,17]nonadec-12-en-7-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C28H35NO4/c1-13-10-14(2)20-21-19(11-13)33-25-16(4)15(3)22-18(12-17-8-6-5-7-9-17)29-27(32)28(22,23(21)25)26(31)24(20)30/h5-10,13,15,18-26,30-31H,4,11-12H2,1-3H3,(H,29,32)/t13-,15-,18+,19-,20+,21?,22+,23+,24-,25-,26-,28-/m1/s1
InChI Key MLMRFXVBCDFIAD-LTMHNWRYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C28H35NO4
Molecular Weight 449.60 g/mol
Exact Mass 449.25660860 g/mol
Topological Polar Surface Area (TPSA) 78.80 Ų
XlogP 2.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Phomopchalasin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 97.28% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.07% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.56% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 92.94% 90.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.12% 91.11%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 89.57% 95.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.89% 97.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.11% 94.45%
CHEMBL4523377 Q86WV6 Stimulator of interferon genes protein 87.09% 95.48%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.20% 99.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.26% 86.33%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.01% 90.71%
CHEMBL3401 O75469 Pregnane X receptor 82.74% 94.73%
CHEMBL4208 P20618 Proteasome component C5 82.24% 90.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.43% 95.89%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.85% 94.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.72% 89.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 80.69% 85.14%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139591043
LOTUS LTS0220207
wikiData Q105166833