Phomaketide B

Details

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Internal ID 2c872342-f757-482d-b949-c44b3b57617a
Taxonomy Organic oxygen compounds > Organooxygen compounds > Alcohols and polyols > Secondary alcohols > Cyclohexanols
IUPAC Name [(1S,2R,3R,4S)-4-(chloromethyl)-4-hydroxy-2-methoxy-3-[(2R,3S)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]cyclohexyl] (E)-3-[(2R,3R)-3-methyloxiran-2-yl]prop-2-enoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H33ClO6/c1-13(2)6-8-17-21(4,29-17)20-19(26-5)16(10-11-22(20,25)12-23)28-18(24)9-7-15-14(3)27-15/h6-7,9,14-17,19-20,25H,8,10-12H2,1-5H3/b9-7+/t14-,15-,16+,17+,19+,20+,21+,22-/m1/s1
InChI Key HVVQOFBOWDNQCO-PIPZUTLJSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C22H33ClO6
Molecular Weight 428.90 g/mol
Exact Mass 428.1965665 g/mol
Topological Polar Surface Area (TPSA) 80.80 Ų
XlogP 2.90

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Phomaketide B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 99.69% 83.82%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.80% 91.11%
CHEMBL3922 P50579 Methionine aminopeptidase 2 97.05% 97.28%
CHEMBL221 P23219 Cyclooxygenase-1 95.78% 90.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.44% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 92.03% 94.45%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.05% 86.33%
CHEMBL340 P08684 Cytochrome P450 3A4 90.33% 91.19%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 88.34% 96.95%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 85.86% 96.77%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 84.48% 95.50%
CHEMBL2664 P23526 Adenosylhomocysteinase 84.21% 86.67%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 84.11% 92.62%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.59% 97.09%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.54% 95.89%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.50% 91.07%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 83.31% 89.05%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.19% 97.14%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.74% 95.89%
CHEMBL5028 O14672 ADAM10 82.69% 97.50%
CHEMBL233 P35372 Mu opioid receptor 81.57% 97.93%
CHEMBL5255 O00206 Toll-like receptor 4 81.33% 92.50%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 80.63% 91.24%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.10% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132526607
LOTUS LTS0110568
wikiData Q105034463