Phepropeptin A

Details

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Internal ID b3cd5303-8c9b-4b26-9cb7-695fbbbcc61e
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name (3R,6S,9S,12R,15S,18S)-3-benzyl-6,12,15-tris(2-methylpropyl)-9-propan-2-yl-1,4,7,10,13,16-hexazabicyclo[16.3.0]henicosane-2,5,8,11,14,17-hexone
SMILES (Canonical) CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2CCCC2C(=O)N1)CC3=CC=CC=C3)CC(C)C)C(C)C)CC(C)C
SMILES (Isomeric) CC(C)C[C@H]1C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N1)CC3=CC=CC=C3)CC(C)C)C(C)C)CC(C)C
InChI InChI=1S/C37H58N6O6/c1-21(2)17-26-32(44)38-28(19-23(5)6)34(46)42-31(24(7)8)36(48)40-27(18-22(3)4)33(45)41-29(20-25-13-10-9-11-14-25)37(49)43-16-12-15-30(43)35(47)39-26/h9-11,13-14,21-24,26-31H,12,15-20H2,1-8H3,(H,38,44)(H,39,47)(H,40,48)(H,41,45)(H,42,46)/t26-,27-,28+,29+,30-,31-/m0/s1
InChI Key QVOWLQGIVUTHGK-ZAFXZDQFSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C37H58N6O6
Molecular Weight 682.90 g/mol
Exact Mass 682.44178359 g/mol
Topological Polar Surface Area (TPSA) 166.00 Ų
XlogP 5.30

Synonyms

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CHEMBL4549827

2D Structure

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2D Structure of Phepropeptin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.84% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.12% 96.09%
CHEMBL3524 P56524 Histone deacetylase 4 96.55% 92.97%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 95.68% 85.14%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 95.21% 97.64%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.78% 95.56%
CHEMBL5103 Q969S8 Histone deacetylase 10 93.56% 90.08%
CHEMBL333 P08253 Matrix metalloproteinase-2 90.73% 96.31%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 90.72% 82.38%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.33% 97.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.30% 95.89%
CHEMBL1902 P62942 FK506-binding protein 1A 88.08% 97.05%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.63% 94.45%
CHEMBL221 P23219 Cyclooxygenase-1 86.27% 90.17%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.76% 97.14%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 84.78% 93.00%
CHEMBL1978 P11511 Cytochrome P450 19A1 84.45% 91.76%
CHEMBL5203 P33316 dUTP pyrophosphatase 83.56% 99.18%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 83.44% 90.93%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.38% 93.03%
CHEMBL3202 P48147 Prolyl endopeptidase 83.23% 90.65%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.21% 96.47%
CHEMBL1293249 Q13887 Kruppel-like factor 5 80.80% 86.33%
CHEMBL228 P31645 Serotonin transporter 80.01% 95.51%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11039712
LOTUS LTS0191092
wikiData Q75059611