Periconin A

Details

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Internal ID 42644c50-9ee6-48bb-a022-cd7f248919f6
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Dipeptides
IUPAC Name 4-[(6-amino-2-oxoazepan-3-yl)amino]-3-[[3-[carboxy(chloro)methyl]-2-chloro-2-(1-chloro-3-hydroxybutyl)cyclopropanecarbonyl]amino]-4-oxobutanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H29Cl3N4O8/c1-7(28)4-11(21)20(23)13(15(22)19(34)35)14(20)18(33)27-10(5-12(29)30)17(32)26-9-3-2-8(24)6-25-16(9)31/h7-11,13-15,28H,2-6,24H2,1H3,(H,25,31)(H,26,32)(H,27,33)(H,29,30)(H,34,35)
InChI Key NFVKVZRRCAVLMX-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C20H29Cl3N4O8
Molecular Weight 559.80 g/mol
Exact Mass 558.105097 g/mol
Topological Polar Surface Area (TPSA) 208.00 Ų
XlogP -3.40

Synonyms

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145586-00-1
4-[(6-amino-2-oxoazepan-3-yl)amino]-3-[[3-[carboxy(chloro)methyl]-2-chloro-2-(1-chloro-3-hydroxybutyl)cyclopropanecarbonyl]amino]-4-oxobutanoic acid
4-((6-amino-2-oxoazepan-3-yl)amino)-3-((3-(carboxy(chloro)methyl)-2-chloro-2-(1-chloro-3-hydroxybutyl)cyclopropanecarbonyl)amino)-4-oxobutanoic acid
RefChem:171750
Periconine A
DTXSID10932646
4-[(3-Amino-7-hydroxy-3,4,5,6-tetrahydro-2H-azepin-6-yl)imino]-3-{[{3-[carboxy(chloro)methyl]-2-chloro-2-(1-chloro-3-hydroxybutyl)cyclopropyl}(hydroxy)methylidene]amino}-4-hydroxybutanoic acid

2D Structure

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2D Structure of Periconin A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL221 P23219 Cyclooxygenase-1 99.26% 90.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.74% 96.09%
CHEMBL2581 P07339 Cathepsin D 98.05% 98.95%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 97.65% 96.38%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.41% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.37% 97.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.51% 91.11%
CHEMBL3468 P55210 Caspase-7 93.48% 95.68%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 93.09% 98.24%
CHEMBL3776 Q14790 Caspase-8 92.06% 97.06%
CHEMBL4040 P28482 MAP kinase ERK2 91.37% 83.82%
CHEMBL5103 Q969S8 Histone deacetylase 10 89.70% 90.08%
CHEMBL2094135 Q96BI3 Gamma-secretase 89.34% 98.05%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 88.71% 96.47%
CHEMBL226 P30542 Adenosine A1 receptor 88.55% 95.93%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 88.05% 89.34%
CHEMBL236 P41143 Delta opioid receptor 88.01% 99.35%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.18% 85.14%
CHEMBL4208 P20618 Proteasome component C5 87.10% 90.00%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 87.00% 88.42%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 86.94% 98.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 86.71% 93.56%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 86.66% 93.03%
CHEMBL4227 P25090 Lipoxin A4 receptor 86.49% 100.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 86.26% 95.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.19% 97.25%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 85.99% 93.00%
CHEMBL259 P32245 Melanocortin receptor 4 84.90% 95.38%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 84.85% 93.10%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.83% 90.71%
CHEMBL2413 P32246 C-C chemokine receptor type 1 83.55% 89.50%
CHEMBL4801 P29466 Caspase-1 82.71% 96.85%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 81.89% 96.90%
CHEMBL3384 Q16512 Protein kinase N1 81.76% 80.71%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 81.64% 91.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 3036128
LOTUS LTS0056518
wikiData Q82908368