Pepstanone A

Details

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Internal ID 9a89c585-fa0d-4cf9-82bc-c89f919f087d
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name 3-hydroxy-6-methyl-4-[[(2S)-3-methyl-1-[[(2S)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]-1-oxobutan-2-yl]amino]-N-[1-[(5-methyl-2-oxohexan-3-yl)amino]-1-oxopropan-2-yl]heptanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C33H61N5O7/c1-17(2)13-24(23(12)39)36-31(43)22(11)34-28(42)16-26(40)25(14-18(3)4)35-29(20(7)8)32(44)38-33(45)30(21(9)10)37-27(41)15-19(5)6/h17-22,24-26,29-30,35,40H,13-16H2,1-12H3,(H,34,42)(H,36,43)(H,37,41)(H,38,44,45)/t22?,24?,25?,26?,29-,30-/m0/s1
InChI Key NUHDIOGRBNJHLE-XVSMXDSJSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C33H61N5O7
Molecular Weight 639.90 g/mol
Exact Mass 639.45709930 g/mol
Topological Polar Surface Area (TPSA) 183.00 Ų
XlogP 3.90

Synonyms

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38752-31-7
L-Valinamide, N-(3-methyl-1-oxobutyl)-L-valyl-N-(4-((2-((1-acetyl-3-methylbutyl)amino)-1-methyl-2-oxoethyl)amino)-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl)-
DTXSID60192031

2D Structure

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2D Structure of Pepstanone A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.44% 98.95%
CHEMBL2094135 Q96BI3 Gamma-secretase 97.12% 98.05%
CHEMBL3308 P55212 Caspase-6 95.87% 97.56%
CHEMBL3776 Q14790 Caspase-8 94.80% 97.06%
CHEMBL4040 P28482 MAP kinase ERK2 94.06% 83.82%
CHEMBL3837 P07711 Cathepsin L 94.02% 96.61%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 92.87% 100.00%
CHEMBL3468 P55210 Caspase-7 91.60% 95.68%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.26% 93.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.17% 96.09%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 89.73% 97.21%
CHEMBL221 P23219 Cyclooxygenase-1 89.17% 90.17%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 86.64% 98.33%
CHEMBL301 P24941 Cyclin-dependent kinase 2 85.87% 91.23%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.33% 99.17%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 84.74% 96.00%
CHEMBL283 P08254 Matrix metalloproteinase 3 84.72% 97.29%
CHEMBL1801 P00747 Plasminogen 84.54% 92.44%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 84.18% 91.11%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 83.69% 97.29%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 82.35% 92.29%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 81.93% 97.23%
CHEMBL2095164 P49354 Geranylgeranyl transferase type I 81.53% 92.80%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.25% 96.47%
CHEMBL2413 P32246 C-C chemokine receptor type 1 81.19% 89.50%
CHEMBL253 P34972 Cannabinoid CB2 receptor 80.80% 97.25%
CHEMBL332 P03956 Matrix metalloproteinase-1 80.74% 94.50%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 80.59% 94.45%
CHEMBL4588 P22894 Matrix metalloproteinase 8 80.36% 94.66%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 80.16% 83.10%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Garcinia multiflora

Cross-Links

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PubChem 56842369
LOTUS LTS0190160
wikiData Q105378987