Penostatin J

Details

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Internal ID 0c091ce7-7ad9-4076-b7c2-cf7579ab90cd
Taxonomy Organic oxygen compounds > Organooxygen compounds > Carbonyl compounds > Cyclic ketones > Cyclohexenones
IUPAC Name (3S,4aR,9aS,9bS)-4a-hydroxy-2-methyl-3-non-1-enyl-3,9,9a,9b-tetrahydrocyclopenta[f]chromen-5-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H30O3/c1-3-4-5-6-7-8-9-13-20-16(2)14-19-18-12-10-11-17(18)15-21(23)22(19,24)25-20/h9-11,13-15,18-20,24H,3-8,12H2,1-2H3/t18-,19+,20+,22-/m1/s1
InChI Key GRTGLCHTLKJYRN-FCIYXJNOSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C22H30O3
Molecular Weight 342.50 g/mol
Exact Mass 342.21949481 g/mol
Topological Polar Surface Area (TPSA) 46.50 Ų
XlogP 4.50

Synonyms

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(3S,4aR,9aS,9bS)-4a-hydroxy-2-methyl-3-non-1-enyl-3,9,9a,9b-tetrahydrocyclopenta(f)chromen-5-one
(3S,4aR,9aS,9bS)-4a-hydroxy-2-methyl-3-non-1-enyl-3,9,9a,9b-tetrahydrocyclopenta[f]chromen-5-one
RefChem:171261
CHEBI:198264
(3S,4aR,9aS,9bS)-4a-hydroxy-2-methyl-3-non-1-enyl-3,9,9a,9b-tetrahydrocyclopenta[]chromen-5-one

2D Structure

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2D Structure of Penostatin J

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 96.91% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.44% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.60% 94.45%
CHEMBL230 P35354 Cyclooxygenase-2 93.26% 89.63%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.84% 96.09%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.62% 95.56%
CHEMBL5979 P05186 Alkaline phosphatase, tissue-nonspecific isozyme 88.61% 85.40%
CHEMBL3060 Q9Y345 Glycine transporter 2 88.60% 99.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 87.70% 97.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 86.75% 90.08%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 86.38% 85.94%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 86.36% 92.08%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.87% 89.00%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 83.91% 92.86%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.82% 99.23%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.05% 93.56%
CHEMBL3401 O75469 Pregnane X receptor 82.64% 94.73%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 81.86% 100.00%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.71% 100.00%
CHEMBL299 P17252 Protein kinase C alpha 80.48% 98.03%
CHEMBL4105838 Q96GG9 DCN1-like protein 1 80.33% 95.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139583319
LOTUS LTS0129608
wikiData Q75059056