Penioxamide A

Details

Top
Internal ID fa4b8c3a-36ac-46c5-a858-adec95175b88
Taxonomy Organoheterocyclic compounds > Quinolines and derivatives > Pyrroloquinolines
IUPAC Name (1S,13R,15S)-12,12-dimethyl-8-(3-methylbut-2-enyl)-10,20,22-triazahexacyclo[13.6.2.01,13.03,11.04,9.015,20]tricosa-3(11),4,6,8-tetraen-23-one
SMILES (Canonical) CC(=CCC1=C2C(=CC=C1)C3=C(N2)C(C4CC56CCCCN5CC4(C3)NC6=O)(C)C)C
SMILES (Isomeric) CC(=CCC1=C2C(=CC=C1)C3=C(N2)C([C@H]4C[C@]56CCCCN5C[C@@]4(C3)NC6=O)(C)C)C
InChI InChI=1S/C27H35N3O/c1-17(2)10-11-18-8-7-9-19-20-14-26-16-30-13-6-5-12-27(30,24(31)29-26)15-21(26)25(3,4)23(20)28-22(18)19/h7-10,21,28H,5-6,11-16H2,1-4H3,(H,29,31)/t21-,26-,27+/m1/s1
InChI Key HUWKBOGWFSCPBJ-ZFWHIUCFSA-N
Popularity 0 references in papers

Physical and Chemical Properties

Top
Molecular Formula C27H35N3O
Molecular Weight 417.60 g/mol
Exact Mass 417.278012748 g/mol
Topological Polar Surface Area (TPSA) 48.10 Ų
XlogP 5.30

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of Penioxamide A

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.59% 98.95%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.44% 94.45%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 98.28% 85.14%
CHEMBL253 P34972 Cannabinoid CB2 receptor 98.14% 97.25%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.31% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.93% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.59% 95.56%
CHEMBL3137262 O60341 LSD1/CoREST complex 95.32% 97.09%
CHEMBL255 P29275 Adenosine A2b receptor 91.98% 98.59%
CHEMBL1937 Q92769 Histone deacetylase 2 91.60% 94.75%
CHEMBL5103 Q969S8 Histone deacetylase 10 91.47% 90.08%
CHEMBL3192 Q9BY41 Histone deacetylase 8 90.27% 93.99%
CHEMBL3310 Q96DB2 Histone deacetylase 11 89.89% 88.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.32% 95.89%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 87.59% 99.23%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 87.46% 93.40%
CHEMBL3922 P50579 Methionine aminopeptidase 2 87.37% 97.28%
CHEMBL221 P23219 Cyclooxygenase-1 86.00% 90.17%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 85.56% 91.71%
CHEMBL284 P27487 Dipeptidyl peptidase IV 85.48% 95.69%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.43% 100.00%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 84.57% 97.50%
CHEMBL2535 P11166 Glucose transporter 83.97% 98.75%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.40% 89.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 82.17% 93.03%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.84% 86.33%
CHEMBL213 P08588 Beta-1 adrenergic receptor 80.39% 95.56%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 122369933
LOTUS LTS0078923
wikiData Q77310102