Penerpene A

Details

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Internal ID 61efa03b-b755-4ff6-a6a1-87426fa4bef7
Taxonomy Lipids and lipid-like molecules > Steroids and steroid derivatives > Oxosteroids
IUPAC Name (3'aS,3'bR,4R,5'aS,7'R,9'bS,11'aS)-9'b-hydroxy-7'-(2-hydroxypropan-2-yl)-3'a,3'b-dimethylspiro[1,2-dihydro-3,1-benzoxazine-4,2'-4,5,5a,10,11,11a-hexahydro-1H-indeno[6,7-f]chromene]-3',8'-dione
SMILES (Canonical) CC12CCC3C(=CC(=O)C(O3)C(C)(C)O)C1(CCC4C2(C(=O)C5(C4)C6=CC=CC=C6NCO5)C)O
SMILES (Isomeric) C[C@]12CC[C@H]3C(=CC(=O)[C@H](O3)C(C)(C)O)[C@@]1(CC[C@@H]4[C@@]2(C(=O)[C@@]5(C4)C6=CC=CC=C6NCO5)C)O
InChI InChI=1S/C28H35NO6/c1-24(2,32)22-20(30)13-18-21(35-22)10-11-25(3)26(4)16(9-12-28(18,25)33)14-27(23(26)31)17-7-5-6-8-19(17)29-15-34-27/h5-8,13,16,21-22,29,32-33H,9-12,14-15H2,1-4H3/t16-,21-,22-,25+,26+,27+,28+/m0/s1
InChI Key LPWZGPBWXQYPSN-IHBLZFHVSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C28H35NO6
Molecular Weight 481.60 g/mol
Exact Mass 481.24643784 g/mol
Topological Polar Surface Area (TPSA) 105.00 Ų
XlogP 2.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Penerpene A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.74% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.53% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.28% 96.09%
CHEMBL2581 P07339 Cathepsin D 94.56% 98.95%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 93.49% 94.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.41% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.18% 97.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.23% 99.23%
CHEMBL3524 P56524 Histone deacetylase 4 91.10% 92.97%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.49% 89.00%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 89.32% 82.69%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 86.92% 94.62%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 86.03% 100.00%
CHEMBL3401 O75469 Pregnane X receptor 84.98% 94.73%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.43% 97.09%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.86% 91.07%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 83.80% 94.45%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 83.57% 97.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.05% 86.33%
CHEMBL1994 P08235 Mineralocorticoid receptor 82.59% 100.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 82.46% 95.89%
CHEMBL4208 P20618 Proteasome component C5 82.35% 90.00%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 80.23% 96.39%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146683210
LOTUS LTS0071904
wikiData Q105155382