Patellamide G

Details

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Internal ID 42aa5c40-b210-4c4e-9530-65f25ddc7b72
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name (4S,7R,8S,11R,18S,21S,24R)-11-benzyl-18-[(2S)-butan-2-yl]-21-[(1S)-1-hydroxyethyl]-7,24-dimethyl-4-(2-methylpropyl)-6-oxa-13,26-dithia-3,10,17,20,23,28,29,30-octazatetracyclo[23.2.1.15,8.112,15]triaconta-1(27),5(30),12(29),14,25(28)-pentaene-2,9,16,19,22-pentone
SMILES (Canonical) CCC(C)C1C(=O)NC(C(=O)NC(C2=NC(=CS2)C(=O)NC(C3=NC(C(O3)C)C(=O)NC(C4=NC(=CS4)C(=O)N1)CC5=CC=CC=C5)CC(C)C)C)C(C)O
SMILES (Isomeric) CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@@H](C2=NC(=CS2)C(=O)N[C@H](C3=N[C@@H]([C@H](O3)C)C(=O)N[C@@H](C4=NC(=CS4)C(=O)N1)CC5=CC=CC=C5)CC(C)C)C)[C@H](C)O
InChI InChI=1S/C38H50N8O7S2/c1-8-19(4)28-33(50)45-29(21(6)47)34(51)39-20(5)37-42-26(16-54-37)31(48)40-24(14-18(2)3)36-46-30(22(7)53-36)35(52)41-25(15-23-12-10-9-11-13-23)38-43-27(17-55-38)32(49)44-28/h9-13,16-22,24-25,28-30,47H,8,14-15H2,1-7H3,(H,39,51)(H,40,48)(H,41,52)(H,44,49)(H,45,50)/t19-,20+,21-,22+,24-,25+,28-,29-,30-/m0/s1
InChI Key VLOXUMQANREDRL-GDCGDAOHSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C38H50N8O7S2
Molecular Weight 795.00 g/mol
Exact Mass 794.32438831 g/mol
Topological Polar Surface Area (TPSA) 270.00 Ų
XlogP 4.80

Synonyms

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218916-91-7
Cyclo(2-((1R)-1-aminoethyl)-4-thiazolecarbonyl-(4S,5R)-2-((1S)-1-amino-3-methylbutyl)-4,5-dihydro-5-methyl-4-oxazolecarbonyl-2-((1R)-1-amino-2-phenylethyl)-4-thiazolecarbonyl-L-isoleucyl-L-threonyl)
CHEMBL447010

2D Structure

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2D Structure of Patellamide G

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.11% 98.95%
CHEMBL221 P23219 Cyclooxygenase-1 95.73% 90.17%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.47% 86.33%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 94.44% 85.14%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.10% 96.09%
CHEMBL3401 O75469 Pregnane X receptor 92.14% 94.73%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 91.26% 97.64%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.23% 95.56%
CHEMBL1949 P62937 Cyclophilin A 90.38% 98.57%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.22% 99.23%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.72% 93.03%
CHEMBL1937 Q92769 Histone deacetylase 2 86.37% 94.75%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 85.51% 95.50%
CHEMBL4447 Q9Y337 Kallikrein 5 83.90% 87.50%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.02% 94.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 82.39% 96.90%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.68% 99.17%
CHEMBL255 P29275 Adenosine A2b receptor 80.66% 98.59%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 44584086
LOTUS LTS0076276
wikiData Q105288546