Pamamycin-635B

Details

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Internal ID 384313b5-a78b-4a7a-9f3e-fdf9f28bfe2e
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (1R,2S,5S,6R,7S,10R,11R,14S,15R,16S)-5-[(1R)-1-[(2R,5S)-5-[(2R)-2-(dimethylamino)pentyl]oxolan-2-yl]ethyl]-2-ethyl-6,11,15-trimethyl-14-propyl-4,13,19,20-tetraoxatricyclo[14.2.1.17,10]icosane-3,12-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C37H65NO7/c1-10-13-26(38(8)9)21-27-15-16-31(41-27)23(5)35-24(6)32-17-18-33(42-32)25(7)36(39)44-29(14-11-2)22(4)30-19-20-34(43-30)28(12-3)37(40)45-35/h22-35H,10-21H2,1-9H3/t22-,23+,24+,25+,26+,27-,28-,29-,30-,31+,32-,33+,34+,35-/m0/s1
InChI Key YKCUFYKQBDKOTO-ZQNVBORHSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C37H65NO7
Molecular Weight 635.90 g/mol
Exact Mass 635.47610341 g/mol
Topological Polar Surface Area (TPSA) 83.50 Ų
XlogP 8.00

Synonyms

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SCHEMBL29884220
CHEBI:203604
(1R,2S,5S,6R,7S,10R,11R,14S,15R,16S)-5-[(1R)-1-[(2R,5S)-5-[(2R)-2-(dimethylamino)pentyl]oxolan-2-yl]ethyl]-2-ethyl-6,11,15-trimethyl-14-propyl-4,13,19,20-tetraoxatricyclo[14.2.1.17,10]icosane-3,12-dione

2D Structure

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2D Structure of Pamamycin-635B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.52% 96.09%
CHEMBL2581 P07339 Cathepsin D 95.68% 98.95%
CHEMBL253 P34972 Cannabinoid CB2 receptor 95.62% 97.25%
CHEMBL255 P29275 Adenosine A2b receptor 90.17% 98.59%
CHEMBL4105838 Q96GG9 DCN1-like protein 1 89.14% 95.00%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 88.05% 96.47%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 87.46% 93.00%
CHEMBL221 P23219 Cyclooxygenase-1 87.20% 90.17%
CHEMBL274 P51681 C-C chemokine receptor type 5 86.54% 98.77%
CHEMBL4072 P07858 Cathepsin B 85.61% 93.67%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.19% 90.71%
CHEMBL3401 O75469 Pregnane X receptor 83.90% 94.73%
CHEMBL4588 P22894 Matrix metalloproteinase 8 83.70% 94.66%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 83.31% 96.38%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.78% 97.09%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 82.24% 98.33%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 82.08% 96.77%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 82.05% 96.21%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 81.31% 91.11%
CHEMBL220 P22303 Acetylcholinesterase 80.84% 94.45%
CHEMBL1806 P11388 DNA topoisomerase II alpha 80.70% 89.00%
CHEMBL2094135 Q96BI3 Gamma-secretase 80.19% 98.05%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 15694391
LOTUS LTS0046672
wikiData Q77379211