Pactamide F

Details

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Internal ID 56b5e712-d688-45e3-96ec-1690984d2928
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Monoterpenoids
IUPAC Name (3E,5R,8S,9S,10S,11S,13R,15S,16R,18Z,25S)-10-(chloromethyl)-11-ethyl-2,10-dihydroxy-21,26-diazapentacyclo[23.2.1.05,16.08,15.09,13]octacosa-1,3,18-triene-20,27,28-trione
SMILES (Canonical) CCC1CC2CC3C(C2C1(CCl)O)CCC4C3CC=CC(=O)NCCCC5C(=O)C(=C(C=C4)O)C(=O)N5
SMILES (Isomeric) CC[C@H]1C[C@H]2C[C@@H]3[C@@H]([C@H]2[C@@]1(CCl)O)CC[C@H]\4[C@H]3C/C=C\C(=O)NCCC[C@H]5C(=O)C(=C(/C=C4)O)C(=O)N5
InChI InChI=1S/C29H39ClN2O5/c1-2-18-13-17-14-21-19-5-3-7-24(34)31-12-4-6-22-27(35)25(28(36)32-22)23(33)11-9-16(19)8-10-20(21)26(17)29(18,37)15-30/h3,7,9,11,16-22,26,33,37H,2,4-6,8,10,12-15H2,1H3,(H,31,34)(H,32,36)/b7-3-,11-9+,25-23?/t16-,17+,18+,19-,20+,21+,22+,26+,29+/m1/s1
InChI Key BRNQMLSKMSMSQY-QLIRVBKLSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C29H39ClN2O5
Molecular Weight 531.10 g/mol
Exact Mass 530.2547500 g/mol
Topological Polar Surface Area (TPSA) 116.00 Ų
XlogP 4.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Pactamide F

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL253 P34972 Cannabinoid CB2 receptor 99.05% 97.25%
CHEMBL1937 Q92769 Histone deacetylase 2 97.20% 94.75%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.32% 94.45%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.64% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 93.16% 97.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 92.47% 93.03%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.42% 90.08%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.03% 96.09%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 91.62% 82.69%
CHEMBL255 P29275 Adenosine A2b receptor 90.21% 98.59%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 90.19% 92.88%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 89.70% 89.34%
CHEMBL2581 P07339 Cathepsin D 89.42% 98.95%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 88.17% 95.50%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 85.88% 92.62%
CHEMBL226 P30542 Adenosine A1 receptor 85.31% 95.93%
CHEMBL218 P21554 Cannabinoid CB1 receptor 85.25% 96.61%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.22% 100.00%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.93% 96.77%
CHEMBL3310 Q96DB2 Histone deacetylase 11 84.20% 88.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 82.14% 89.00%
CHEMBL3012 Q13946 Phosphodiesterase 7A 81.43% 99.29%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.90% 91.07%
CHEMBL3045 P05771 Protein kinase C beta 80.65% 97.63%
CHEMBL299 P17252 Protein kinase C alpha 80.55% 98.03%
CHEMBL2996 Q05655 Protein kinase C delta 80.48% 97.79%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 80.23% 96.90%
CHEMBL4530 P00488 Coagulation factor XIII 80.00% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684580
LOTUS LTS0048799
wikiData Q104944931