Pachyclavulariolide M

Details

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Internal ID 6c5a1cd7-4a51-4194-aed0-93e4110851ee
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Tricarboxylic acids and derivatives
IUPAC Name [(1S,2R,3S,8R,10R,12R,15S,16R)-2-acetyloxy-8-hydroxy-1,5,10,15-tetramethyl-6-oxo-7,11,19-trioxatetracyclo[14.2.1.04,8.010,12]nonadec-4-en-3-yl] acetate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C24H34O9/c1-12-7-8-17-23(6,32-17)11-24(28)18(13(2)21(27)33-24)19(29-14(3)25)20(30-15(4)26)22(5)10-9-16(12)31-22/h12,16-17,19-20,28H,7-11H2,1-6H3/t12-,16+,17+,19-,20+,22-,23+,24+/m0/s1
InChI Key ZDWIWCIAHNELKV-BSUPVGLKSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C24H34O9
Molecular Weight 466.50 g/mol
Exact Mass 466.22028266 g/mol
Topological Polar Surface Area (TPSA) 121.00 Ų
XlogP 1.30

Synonyms

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((1S,2R,3S,8R,10R,12R,15S,16R)-2-acetyloxy-8-hydroxy-1,5,10,15-tetramethyl-6-oxo-7,11,19-trioxatetracyclo(14.2.1.04,8.010,12)nonadec-4-en-3-yl) acetate
[(1S,2R,3S,8R,10R,12R,15S,16R)-2-acetyloxy-8-hydroxy-1,5,10,15-tetramethyl-6-oxo-7,11,19-trioxatetracyclo[14.2.1.04,8.010,12]nonadec-4-en-3-yl] acetate
RefChem:169446
551938-76-2
CHEMBL468866

2D Structure

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2D Structure of Pachyclavulariolide M

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.00% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.36% 91.11%
CHEMBL2581 P07339 Cathepsin D 92.43% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 92.19% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 91.02% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.62% 99.23%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 89.39% 94.45%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 88.79% 82.69%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 88.27% 97.14%
CHEMBL1293249 Q13887 Kruppel-like factor 5 88.08% 86.33%
CHEMBL340 P08684 Cytochrome P450 3A4 87.12% 91.19%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.26% 97.25%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.37% 89.00%
CHEMBL5028 O14672 ADAM10 82.86% 97.50%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.65% 93.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 81.16% 97.09%
CHEMBL1293294 P51151 Ras-related protein Rab-9A 80.90% 87.67%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10457255
LOTUS LTS0122055
wikiData Q105372797