(7R,8R,10S)-10-((3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-7,8,9,10-tetrahydro-1,6,7,8,11-pentahydroxy-5,12-naphthacenedione

Details

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Internal ID 49c13b9c-be2a-48e0-b3fa-bae6cd16f9e5
Taxonomy Phenylpropanoids and polyketides > Anthracyclines
IUPAC Name (7S,9R,10R)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9,10,11-pentahydroxy-8,10-dihydro-7H-tetracene-5,12-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C26H29NO10/c1-3-26(35)8-13(37-14-7-11(27)20(29)9(2)36-14)16-19(25(26)34)24(33)17-18(23(16)32)22(31)15-10(21(17)30)5-4-6-12(15)28/h4-6,9,11,13-14,20,25,28-29,32-35H,3,7-8,27H2,1-2H3/t9-,11-,13-,14-,20+,25+,26+/m0/s1
InChI Key LKBBOPGQDRPCDS-YAOXHJNESA-N
Popularity 8 references in papers

Physical and Chemical Properties

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Molecular Formula C26H29NO10
Molecular Weight 515.50 g/mol
Exact Mass 515.17914612 g/mol
Topological Polar Surface Area (TPSA) 200.00 Ų
XlogP 1.60

Synonyms

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105615-58-5
AJ227FR53I
10-epi-Oxaunomycin
7-O-(alpha-L-Daunosaminyl)-beta-rhodomycinone
UNII-AJ227FR53I
DTXSID70909632
R 20X2
(7S,9R,10R)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-9-ethyl-4,6,9,10,11-pentahydroxy-8,10-dihydro-7H-tetracene-5,12-dione
5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-7,8,9,10-tetrahydro-1,6,7,8,11-pentahydroxy-
5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-1,6,7,8,11-pentahydroxy-, (8S-cis)-
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of (7R,8R,10S)-10-((3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-ethyl-7,8,9,10-tetrahydro-1,6,7,8,11-pentahydroxy-5,12-naphthacenedione

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.88% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 98.78% 97.09%
CHEMBL2581 P07339 Cathepsin D 97.94% 98.95%
CHEMBL226 P30542 Adenosine A1 receptor 97.46% 95.93%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.96% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 96.46% 89.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.35% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 92.15% 86.33%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 92.00% 96.38%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.87% 99.23%
CHEMBL1951 P21397 Monoamine oxidase A 90.77% 91.49%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.68% 95.89%
CHEMBL221 P23219 Cyclooxygenase-1 90.65% 90.17%
CHEMBL2996 Q05655 Protein kinase C delta 89.29% 97.79%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 88.87% 94.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 87.38% 92.88%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 87.18% 96.95%
CHEMBL3492 P49721 Proteasome Macropain subunit 85.82% 90.24%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.74% 100.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 85.66% 92.94%
CHEMBL4208 P20618 Proteasome component C5 84.94% 90.00%
CHEMBL3401 O75469 Pregnane X receptor 80.80% 94.73%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 159300
LOTUS LTS0064317
wikiData Q82879275