Opacaline A

Details

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Internal ID f842d67e-a5de-48c3-9fac-1f36d5e0986f
Taxonomy Alkaloids and derivatives > Harmala alkaloids
IUPAC Name 2-[4-(7-bromo-9H-pyrido[3,4-b]indol-1-yl)butyl]guanidine
SMILES (Canonical) C1=CC2=C(C=C1Br)NC3=C2C=CN=C3CCCCN=C(N)N
SMILES (Isomeric) C1=CC2=C(C=C1Br)NC3=C2C=CN=C3CCCCN=C(N)N
InChI InChI=1S/C16H18BrN5/c17-10-4-5-11-12-6-8-20-13(15(12)22-14(11)9-10)3-1-2-7-21-16(18)19/h4-6,8-9,22H,1-3,7H2,(H4,18,19,21)
InChI Key RYDDJEFQYPXRAF-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C16H18BrN5
Molecular Weight 360.25 g/mol
Exact Mass 359.07456 g/mol
Topological Polar Surface Area (TPSA) 93.10 Ų
XlogP 3.30

Synonyms

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CHEMBL1821995

2D Structure

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2D Structure of Opacaline A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2292 Q13627 Dual-specificity tyrosine-phosphorylation regulated kinase 1A 98.87% 93.24%
CHEMBL1951 P21397 Monoamine oxidase A 98.55% 91.49%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.33% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.32% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.69% 94.45%
CHEMBL240 Q12809 HERG 96.81% 89.76%
CHEMBL255 P29275 Adenosine A2b receptor 95.67% 98.59%
CHEMBL1781 P11387 DNA topoisomerase I 93.70% 97.00%
CHEMBL3286 P00749 Urokinase-type plasminogen activator 90.53% 97.88%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 89.64% 89.62%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.42% 86.33%
CHEMBL5443 O00311 Cell division cycle 7-related protein kinase 86.92% 96.11%
CHEMBL2885 P07451 Carbonic anhydrase III 85.78% 87.45%
CHEMBL202 P00374 Dihydrofolate reductase 85.20% 89.92%
CHEMBL3060 Q9Y345 Glycine transporter 2 84.86% 99.17%
CHEMBL241 Q14432 Phosphodiesterase 3A 84.73% 92.94%
CHEMBL2535 P11166 Glucose transporter 84.65% 98.75%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.61% 94.00%
CHEMBL4208 P20618 Proteasome component C5 84.30% 90.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.47% 89.00%
CHEMBL213 P08588 Beta-1 adrenergic receptor 83.40% 95.56%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.20% 96.00%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 80.82% 91.71%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 80.61% 97.23%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 80.52% 86.92%
CHEMBL2581 P07339 Cathepsin D 80.27% 98.95%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 54669752
LOTUS LTS0099423
wikiData Q105247492