Trichogin A IV

Details

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Internal ID aea9f220-fd47-445b-af64-16ae7f14bcec
Taxonomy Organic Polymers > Polypeptides
IUPAC Name N-[1-[[2-[[(2S)-1-[[1-[[2-[[2-[[(2S)-1-[[1-[[2-[[(2S,3S)-1-[[(2S)-1-hydroxy-4-methylpentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-2-methyl-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-2-methyl-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-2-methyl-1-oxopropan-2-yl]octanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C52H95N11O12/c1-16-18-19-20-21-22-38(65)61-50(10,11)47(73)55-28-41(68)59-37(25-33(7)8)45(71)62-51(12,13)48(74)54-26-39(66)53-27-40(67)58-36(24-32(5)6)44(70)63-52(14,15)49(75)56-29-42(69)60-43(34(9)17-2)46(72)57-35(30-64)23-31(3)4/h31-37,43,64H,16-30H2,1-15H3,(H,53,66)(H,54,74)(H,55,73)(H,56,75)(H,57,72)(H,58,67)(H,59,68)(H,60,69)(H,61,65)(H,62,71)(H,63,70)/t34-,35-,36-,37-,43-/m0/s1
InChI Key LZAAXJCEERCDPT-CKFFZNTQSA-N
Popularity 10 references in papers

Physical and Chemical Properties

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Molecular Formula C52H95N11O12
Molecular Weight 1066.40 g/mol
Exact Mass 1065.71616751 g/mol
Topological Polar Surface Area (TPSA) 340.00 Ų
XlogP 4.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Trichogin A IV

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.87% 98.95%
CHEMBL3837 P07711 Cathepsin L 98.65% 96.61%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 98.41% 97.29%
CHEMBL230 P35354 Cyclooxygenase-2 98.09% 89.63%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.05% 99.17%
CHEMBL3359 P21462 Formyl peptide receptor 1 96.92% 93.56%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 95.83% 96.95%
CHEMBL299 P17252 Protein kinase C alpha 94.92% 98.03%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 94.62% 100.00%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 93.83% 97.21%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.26% 97.25%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 93.04% 92.08%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 91.76% 97.23%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 91.50% 98.94%
CHEMBL236 P41143 Delta opioid receptor 91.25% 99.35%
CHEMBL5979 P05186 Alkaline phosphatase, tissue-nonspecific isozyme 91.13% 85.40%
CHEMBL2664 P23526 Adenosylhomocysteinase 90.95% 86.67%
CHEMBL2514 O95665 Neurotensin receptor 2 90.92% 100.00%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 90.47% 96.67%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 89.96% 96.09%
CHEMBL4227 P25090 Lipoxin A4 receptor 89.84% 100.00%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 89.64% 95.71%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 89.63% 89.33%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 88.79% 92.86%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 88.62% 90.24%
CHEMBL1944495 P28065 Proteasome subunit beta type-9 87.87% 97.50%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 87.56% 96.90%
CHEMBL220 P22303 Acetylcholinesterase 87.43% 94.45%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 86.86% 98.33%
CHEMBL2885 P07451 Carbonic anhydrase III 86.79% 87.45%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.70% 96.47%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 86.62% 91.81%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 86.58% 92.29%
CHEMBL3238 P23786 Carnitine palmitoyltransferase 2 86.01% 94.05%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 85.62% 96.00%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 85.27% 92.88%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.27% 90.71%
CHEMBL2996 Q05655 Protein kinase C delta 85.05% 97.79%
CHEMBL2265 P23141 Acyl coenzyme A:cholesterol acyltransferase 84.42% 85.94%
CHEMBL340 P08684 Cytochrome P450 3A4 84.34% 91.19%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.25% 97.14%
CHEMBL3468 P55210 Caspase-7 83.96% 95.68%
CHEMBL3176 O43603 Galanin receptor 2 83.87% 98.89%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 83.79% 91.24%
CHEMBL4662 P28074 Proteasome Macropain subunit MB1 82.85% 93.85%
CHEMBL260 Q16539 MAP kinase p38 alpha 82.76% 97.78%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 82.54% 94.33%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 82.53% 100.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 82.52% 91.11%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 81.53% 95.00%
CHEMBL3776 Q14790 Caspase-8 81.00% 97.06%
CHEMBL3401 O75469 Pregnane X receptor 80.88% 94.73%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 80.06% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 15886478
LOTUS LTS0185753
wikiData Q77373021