Notoamide N

Details

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Internal ID c207ab18-7f94-439a-b46c-c2595c147290
Taxonomy Organoheterocyclic compounds > Benzopyrans > 1-benzopyrans > 2,2-dimethyl-1-benzopyrans
IUPAC Name (1'S,3R,7'S,9'S)-5-chloro-7,7,10',10'-tetramethylspiro[1H-pyrano[2,3-g]indole-3,11'-3,13-diazatetracyclo[5.5.2.01,9.03,7]tetradecane]-2,2',14'-trione
SMILES (Canonical) CC1(C=CC2=C3C(=CC(=C2O1)Cl)C4(CC56C(C4(C)C)CC7(CCCN7C5=O)C(=O)N6)C(=O)N3)C
SMILES (Isomeric) CC1(C=CC2=C3C(=CC(=C2O1)Cl)[C@]4(C[C@]56[C@H](C4(C)C)C[C@@]7(CCCN7C5=O)C(=O)N6)C(=O)N3)C
InChI InChI=1S/C26H28ClN3O4/c1-22(2)8-6-13-17-14(10-15(27)18(13)34-22)25(20(32)28-17)12-26-16(23(25,3)4)11-24(19(31)29-26)7-5-9-30(24)21(26)33/h6,8,10,16H,5,7,9,11-12H2,1-4H3,(H,28,32)(H,29,31)/t16-,24-,25+,26-/m0/s1
InChI Key OYYJASXCEOMRMB-GZCJIMSASA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C26H28ClN3O4
Molecular Weight 482.00 g/mol
Exact Mass 481.1768341 g/mol
Topological Polar Surface Area (TPSA) 87.70 Ų
XlogP 2.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Notoamide N

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.64% 94.45%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 98.24% 93.40%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.16% 91.11%
CHEMBL4835 P00338 L-lactate dehydrogenase A chain 94.84% 95.34%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.48% 96.09%
CHEMBL2581 P07339 Cathepsin D 94.39% 98.95%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 94.30% 96.77%
CHEMBL253 P34972 Cannabinoid CB2 receptor 93.30% 97.25%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.24% 86.33%
CHEMBL238 Q01959 Dopamine transporter 90.41% 95.88%
CHEMBL3012 Q13946 Phosphodiesterase 7A 90.33% 99.29%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.51% 95.56%
CHEMBL4208 P20618 Proteasome component C5 89.27% 90.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 88.61% 93.99%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 88.43% 82.69%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 87.57% 90.24%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.37% 90.71%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 85.89% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 85.71% 97.09%
CHEMBL1914 P06276 Butyrylcholinesterase 85.39% 95.00%
CHEMBL1937 Q92769 Histone deacetylase 2 85.07% 94.75%
CHEMBL4829 O00763 Acetyl-CoA carboxylase 2 84.04% 98.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 83.65% 91.03%
CHEMBL218 P21554 Cannabinoid CB1 receptor 83.20% 96.61%
CHEMBL1806 P11388 DNA topoisomerase II alpha 81.10% 89.00%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.89% 94.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.27% 97.14%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.19% 95.89%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 101463300
LOTUS LTS0232926
wikiData Q77509855