Nostoweipeptin W4

Details

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Internal ID 6dd5de55-4554-4055-b001-54e0fac2f515
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (2S)-2-acetamido-N-[(1S,5R,7S,11S,13S,21S,23S,26R,29S,32S,39R)-29-[(2S)-butan-2-yl]-5,39-dihydroxy-35-(hydroxymethyl)-32-[(4-hydroxyphenyl)methyl]-11,21-dimethyl-26-(2-methylpropyl)-2,8,14,18,24,27,30,33,36-nonaoxo-15-oxa-3,9,19,25,28,31,34,37-octazapentacyclo[35.3.0.03,7.09,13.019,23]tetracontan-17-yl]-3-phenylpropanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C60H84N10O16/c1-8-34(6)50-55(80)63-43(22-37-14-16-38(73)17-15-37)52(77)64-44(29-71)56(81)69-27-39(74)23-47(69)59(84)70-28-40(75)24-48(70)58(83)68-26-33(5)20-49(68)60(85)86-30-45(65-51(76)42(61-35(7)72)21-36-12-10-9-11-13-36)57(82)67-25-32(4)19-46(67)54(79)62-41(18-31(2)3)53(78)66-50/h9-17,31-34,39-50,71,73-75H,8,18-30H2,1-7H3,(H,61,72)(H,62,79)(H,63,80)(H,64,77)(H,65,76)(H,66,78)/t32-,33-,34-,39+,40+,41+,42-,43-,44?,45?,46-,47-,48-,49-,50-/m0/s1
InChI Key VZRGRTLNYUOHNX-DPFCJGTLSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C60H84N10O16
Molecular Weight 1201.40 g/mol
Exact Mass 1200.60667663 g/mol
Topological Polar Surface Area (TPSA) 363.00 Ų
XlogP 2.10

Synonyms

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DTXSID801098092

2D Structure

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2D Structure of Nostoweipeptin W4

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.98% 98.95%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 98.51% 90.93%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 97.95% 97.64%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.55% 96.09%
CHEMBL3837 P07711 Cathepsin L 97.50% 96.61%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 97.27% 97.14%
CHEMBL1801 P00747 Plasminogen 95.26% 92.44%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.69% 94.45%
CHEMBL4072 P07858 Cathepsin B 94.26% 93.67%
CHEMBL3060 Q9Y345 Glycine transporter 2 94.20% 99.17%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 93.15% 95.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.88% 90.08%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 91.48% 91.71%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.38% 97.09%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 91.37% 95.89%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 90.68% 82.38%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 89.26% 95.56%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.23% 93.56%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 89.08% 93.00%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 88.42% 95.50%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 88.04% 97.23%
CHEMBL221 P23219 Cyclooxygenase-1 87.59% 90.17%
CHEMBL226 P30542 Adenosine A1 receptor 87.08% 95.93%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 86.84% 96.90%
CHEMBL259 P32245 Melanocortin receptor 4 85.70% 95.38%
CHEMBL340 P08684 Cytochrome P450 3A4 84.92% 91.19%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.78% 89.00%
CHEMBL216 P11229 Muscarinic acetylcholine receptor M1 84.42% 94.23%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.84% 86.33%
CHEMBL3891 P07384 Calpain 1 83.75% 93.04%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.57% 99.23%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 83.07% 91.11%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 82.04% 91.81%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 81.98% 90.71%
CHEMBL2413 P32246 C-C chemokine receptor type 1 81.95% 89.50%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 81.76% 100.00%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 81.56% 96.11%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 81.13% 95.83%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 80.26% 100.00%
CHEMBL2514 O95665 Neurotensin receptor 2 80.24% 100.00%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 80.20% 85.11%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146683678
LOTUS LTS0190337
wikiData Q105299942