Nostocyclopeptide A1

Details

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Internal ID 629c8c64-05b2-42ad-b599-9887b729b0a5
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Cyclic peptides
IUPAC Name 3-[(3S,6S,9R,15S,18S,21S,23S)-6-[(2S)-butan-2-yl]-3-(hydroxymethyl)-15-[(4-hydroxyphenyl)methyl]-23-methyl-18-(2-methylpropyl)-2,5,8,11,14,20-hexaoxo-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracos-16-en-9-yl]propanamide
SMILES (Canonical) CCC(C)C1C(=O)NC(C(=O)N2CC(CC2C(=O)NC(C=NC(C(=O)NCC(=O)NC(C(=O)N1)CCC(=O)N)CC3=CC=C(C=C3)O)CC(C)C)C)CO
SMILES (Isomeric) CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N2C[C@H](C[C@H]2C(=O)N[C@H](C=N[C@H](C(=O)NCC(=O)N[C@@H](C(=O)N1)CCC(=O)N)CC3=CC=C(C=C3)O)CC(C)C)C)CO
InChI InChI=1S/C37H56N8O9/c1-6-22(5)32-36(53)43-28(19-46)37(54)45-18-21(4)14-29(45)35(52)41-24(13-20(2)3)16-39-27(15-23-7-9-25(47)10-8-23)33(50)40-17-31(49)42-26(34(51)44-32)11-12-30(38)48/h7-10,16,20-22,24,26-29,32,46-47H,6,11-15,17-19H2,1-5H3,(H2,38,48)(H,40,50)(H,41,52)(H,42,49)(H,43,53)(H,44,51)/t21-,22-,24-,26+,27-,28-,29-,32-/m0/s1
InChI Key TZHROWIOAVYSMP-NMMVZENQSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C37H56N8O9
Molecular Weight 756.90 g/mol
Exact Mass 756.41702539 g/mol
Topological Polar Surface Area (TPSA) 262.00 Ų
XlogP 1.00

Synonyms

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DTXSID701334574
3-((3S,6S,9R,15S,18S,21S,23S)-6-((2S)-butan-2-yl)-3-(hydroxymethyl)-15-((4-hydroxyphenyl)methyl)-23-methyl-18-(2-methylpropyl)-2,5,8,11,14,20-hexaoxo-1,4,7,10,13,16,19-heptazabicyclo(19.3.0)tetracos-16-en-9-yl)propanamide
3-[(3S,6S,9R,15S,18S,21S,23S)-6-[(2S)-butan-2-yl]-3-(hydroxymethyl)-15-[(4-hydroxyphenyl)methyl]-23-methyl-18-(2-methylpropyl)-2,5,8,11,14,20-hexaoxo-1,4,7,10,13,16,19-heptazabicyclo[19.3.0]tetracos-16-en-9-yl]propanamide
RefChem:166760
DTXCID501763993
CHEBI:80053
CHEMBL451336
SCHEMBL17866796
BDBM50478553
Q27149204
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Nostocyclopeptide A1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.56% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.35% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.44% 94.45%
CHEMBL253 P34972 Cannabinoid CB2 receptor 97.35% 97.25%
CHEMBL4040 P28482 MAP kinase ERK2 96.43% 83.82%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.56% 97.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.29% 91.11%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 92.23% 99.09%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 92.14% 93.10%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 92.11% 100.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 91.31% 99.17%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 90.99% 90.71%
CHEMBL5103 Q969S8 Histone deacetylase 10 90.58% 90.08%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.47% 86.33%
CHEMBL4506 Q96EB6 NAD-dependent deacetylase sirtuin 1 89.61% 88.33%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 89.44% 93.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.33% 95.89%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 87.97% 96.90%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 87.71% 95.00%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 87.23% 82.38%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 87.18% 82.69%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 86.81% 97.64%
CHEMBL2443 P49862 Kallikrein 7 86.53% 94.00%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 85.93% 97.23%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 85.72% 95.89%
CHEMBL6175 Q9H3R0 Lysine-specific demethylase 4C 84.04% 96.69%
CHEMBL2996 Q05655 Protein kinase C delta 81.64% 97.79%
CHEMBL3359 P21462 Formyl peptide receptor 1 81.57% 93.56%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 81.38% 90.93%
CHEMBL4071 P08311 Cathepsin G 81.11% 94.64%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10652683
LOTUS LTS0053777
wikiData Q105268196