Nodulisporic acid D1

Details

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Internal ID cc5833ac-7ab6-4a5a-a4ec-9906f7d61f2b
Taxonomy Organoheterocyclic compounds > Naphthofurans
IUPAC Name (E)-3-[(2S,3S,6S,8S,10S,11R,14S,25S)-6-hydroxy-2,3,10,22,22,24,24-heptamethyl-7,23-dioxa-30-azaoctacyclo[14.14.0.02,14.03,11.06,10.017,29.019,27.020,25]triaconta-1(16),17(29),18,20,27-pentaen-8-yl]-2-methylprop-2-enoic acid
SMILES (Canonical) CC(=CC1CC2(C3CCC4CC5=C(C4(C3(CCC2(O1)O)C)C)NC6=C5C=C7C(=C6)CC8C7=CC(OC8(C)C)(C)C)C)C(=O)O
SMILES (Isomeric) C/C(=C\[C@@H]1C[C@]2([C@@H]3CC[C@H]4CC5=C([C@@]4([C@]3(CC[C@@]2(O1)O)C)C)NC6=C5C=C7C(=C6)C[C@H]8C7=CC(OC8(C)C)(C)C)C)/C(=O)O
InChI InChI=1S/C38H49NO5/c1-20(32(40)41)13-23-18-36(7)30-10-9-22-16-26-25-17-24-21(14-28-27(24)19-33(2,3)44-34(28,4)5)15-29(25)39-31(26)37(22,8)35(30,6)11-12-38(36,42)43-23/h13,15,17,19,22-23,28,30,39,42H,9-12,14,16,18H2,1-8H3,(H,40,41)/b20-13+/t22-,23+,28-,30+,35-,36-,37+,38-/m0/s1
InChI Key NEINCGYMLGLOMN-GXZGSLQHSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C38H49NO5
Molecular Weight 599.80 g/mol
Exact Mass 599.36107366 g/mol
Topological Polar Surface Area (TPSA) 91.80 Ų
XlogP 6.50

Synonyms

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CHEMBL451879

2D Structure

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2D Structure of Nodulisporic acid D1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.85% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.06% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.28% 94.45%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 94.12% 94.80%
CHEMBL217 P14416 Dopamine D2 receptor 93.99% 95.62%
CHEMBL1806 P11388 DNA topoisomerase II alpha 93.92% 89.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.95% 95.56%
CHEMBL241 Q14432 Phosphodiesterase 3A 92.81% 92.94%
CHEMBL1994 P08235 Mineralocorticoid receptor 91.00% 100.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.32% 97.09%
CHEMBL340 P08684 Cytochrome P450 3A4 89.96% 91.19%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.49% 95.89%
CHEMBL2581 P07339 Cathepsin D 89.34% 98.95%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 87.44% 94.62%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 87.32% 90.95%
CHEMBL1937 Q92769 Histone deacetylase 2 87.19% 94.75%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 86.57% 89.05%
CHEMBL3922 P50579 Methionine aminopeptidase 2 85.89% 97.28%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 84.99% 91.79%
CHEMBL3351 Q13085 Acetyl-CoA carboxylase 1 84.81% 93.04%
CHEMBL1951 P21397 Monoamine oxidase A 84.54% 91.49%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 84.28% 96.77%
CHEMBL1293249 Q13887 Kruppel-like factor 5 83.66% 86.33%
CHEMBL1163125 O60885 Bromodomain-containing protein 4 82.98% 97.31%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.62% 99.23%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 80.16% 97.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11753691
LOTUS LTS0082977
wikiData Q75062982