Nocardimicin I

Details

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Internal ID ba6e0084-34f5-4287-8080-3efa6d419f56
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides
IUPAC Name [1-[(1-hydroxy-2-oxoazepan-3-yl)amino]-2-methyl-1-oxoicosan-3-yl] 6-[formyl(hydroxy)amino]-2-[[2-(2-hydroxyphenyl)-4,5-dihydro-1,3-oxazole-4-carbonyl]amino]hexanoate
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C44H71N5O10/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-28-39(33(2)40(52)45-35-25-21-23-30-49(57)43(35)54)59-44(55)36(26-20-22-29-48(56)32-50)46-41(53)37-31-58-42(47-37)34-24-18-19-27-38(34)51/h18-19,24,27,32-33,35-37,39,51,56-57H,3-17,20-23,25-26,28-31H2,1-2H3,(H,45,52)(H,46,53)
InChI Key JLURERWJFCNPBC-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C44H71N5O10
Molecular Weight 830.10 g/mol
Exact Mass 829.52009348 g/mol
Topological Polar Surface Area (TPSA) 207.00 Ų
XlogP 9.30

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Nocardimicin I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.92% 98.95%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 98.15% 93.10%
CHEMBL3359 P21462 Formyl peptide receptor 1 97.61% 93.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.44% 96.09%
CHEMBL5103 Q969S8 Histone deacetylase 10 96.81% 90.08%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 95.66% 91.81%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 95.64% 98.33%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 95.32% 82.69%
CHEMBL3060 Q9Y345 Glycine transporter 2 94.53% 99.17%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.02% 95.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 92.17% 90.71%
CHEMBL5028 O14672 ADAM10 91.34% 97.50%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.32% 99.23%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 90.30% 97.64%
CHEMBL3891 P07384 Calpain 1 89.03% 93.04%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.04% 89.00%
CHEMBL4227 P25090 Lipoxin A4 receptor 88.03% 100.00%
CHEMBL321 P14780 Matrix metalloproteinase 9 87.96% 92.12%
CHEMBL4072 P07858 Cathepsin B 87.13% 93.67%
CHEMBL5608 Q16288 NT-3 growth factor receptor 86.47% 95.89%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 85.04% 96.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.99% 97.14%
CHEMBL226 P30542 Adenosine A1 receptor 84.36% 95.93%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.00% 97.09%
CHEMBL221 P23219 Cyclooxygenase-1 82.54% 90.17%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 81.43% 83.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 81.21% 91.11%
CHEMBL2514 O95665 Neurotensin receptor 2 81.19% 100.00%
CHEMBL340 P08684 Cytochrome P450 3A4 80.71% 91.19%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 80.48% 95.83%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 80.47% 96.25%
CHEMBL5255 O00206 Toll-like receptor 4 80.02% 92.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 136814269
LOTUS LTS0073898
wikiData Q77379783