Nikkomycin QZ

Details

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Internal ID df2fdba7-6a74-442e-8813-cba94f38a4f9
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
IUPAC Name (2R)-2-[[(2R)-2-[[(2S,3S,4R)-2-amino-4-hydroxy-4-(5-hydroxypyridin-2-yl)-3-methylbutanoyl]amino]-2-[(2R,3R,4S,5S)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]acetyl]amino]-4-hydroxybutanoic acid
SMILES (Canonical) CC(C(C1=NC=C(C=C1)O)O)C(C(=O)NC(C2C(C(C(O2)N3C=CC(=O)NC3=O)O)O)C(=O)NC(CCO)C(=O)O)N
SMILES (Isomeric) C[C@H]([C@H](C1=NC=C(C=C1)O)O)[C@@H](C(=O)N[C@H]([C@@H]2[C@@H]([C@@H]([C@H](O2)N3C=CC(=O)NC3=O)O)O)C(=O)N[C@H](CCO)C(=O)O)N
InChI InChI=1S/C24H32N6O12/c1-9(16(34)11-3-2-10(32)8-26-11)14(25)20(37)29-15(21(38)27-12(5-7-31)23(39)40)19-17(35)18(36)22(42-19)30-6-4-13(33)28-24(30)41/h2-4,6,8-9,12,14-19,22,31-32,34-36H,5,7,25H2,1H3,(H,27,38)(H,29,37)(H,39,40)(H,28,33,41)/t9-,12+,14-,15+,16+,17+,18-,19+,22-/m0/s1
InChI Key QUPFUBWPUBLIHU-DDVQFXSFSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C24H32N6O12
Molecular Weight 596.50 g/mol
Exact Mass 596.20782048 g/mol
Topological Polar Surface Area (TPSA) 294.00 Ų
XlogP -6.50

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Nikkomycin QZ

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.30% 96.09%
CHEMBL2581 P07339 Cathepsin D 98.36% 98.95%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 97.89% 93.10%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.01% 85.14%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.09% 94.45%
CHEMBL4040 P28482 MAP kinase ERK2 94.60% 83.82%
CHEMBL3060 Q9Y345 Glycine transporter 2 94.37% 99.17%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 93.30% 92.29%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 92.46% 90.71%
CHEMBL226 P30542 Adenosine A1 receptor 90.90% 95.93%
CHEMBL3359 P21462 Formyl peptide receptor 1 89.39% 93.56%
CHEMBL255 P29275 Adenosine A2b receptor 86.96% 98.59%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 86.86% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.25% 99.23%
CHEMBL3401 O75469 Pregnane X receptor 86.01% 94.73%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 85.83% 99.15%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 85.64% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 84.68% 89.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.94% 95.89%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 83.34% 100.00%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 81.86% 95.00%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 81.42% 94.62%
CHEMBL2535 P11166 Glucose transporter 80.90% 98.75%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 80.48% 94.08%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139589027
LOTUS LTS0121367
wikiData Q105228333