Nikkomycin Lz

Details

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Internal ID bfe84de0-817f-4c94-bf4d-59e122381cd2
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides
IUPAC Name 2-[(2-amino-4-hydroxy-3-methyl-4-pyridin-2-ylbutanoyl)amino]-2-[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid
SMILES (Canonical) CC(C(C1=CC=CC=N1)O)C(C(=O)NC(C2C(C(C(O2)N3C=CC(=O)NC3=O)O)O)C(=O)O)N
SMILES (Isomeric) CC(C(C1=CC=CC=N1)O)C(C(=O)NC(C2C(C(C(O2)N3C=CC(=O)NC3=O)O)O)C(=O)O)N
InChI InChI=1S/C20H25N5O9/c1-8(13(27)9-4-2-3-6-22-9)11(21)17(30)24-12(19(31)32)16-14(28)15(29)18(34-16)25-7-5-10(26)23-20(25)33/h2-8,11-16,18,27-29H,21H2,1H3,(H,24,30)(H,31,32)(H,23,26,33)
InChI Key HYBLVRJOBLCCCY-UHFFFAOYSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C20H25N5O9
Molecular Weight 479.40 g/mol
Exact Mass 479.16522739 g/mol
Topological Polar Surface Area (TPSA) 225.00 Ų
XlogP -5.20

Synonyms

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2-[(2-Amino-4-hydroxy-3-methyl-4-pyridin-2-ylbutanoyl)amino]-2-[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]acetic acid

2D Structure

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2D Structure of Nikkomycin Lz

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.07% 96.09%
CHEMBL2581 P07339 Cathepsin D 98.38% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 97.17% 85.14%
CHEMBL4040 P28482 MAP kinase ERK2 97.13% 83.82%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 91.27% 100.00%
CHEMBL3401 O75469 Pregnane X receptor 91.04% 94.73%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 90.92% 93.10%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.78% 99.23%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.86% 95.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.68% 89.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.45% 90.71%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 83.12% 94.08%
CHEMBL5028 O14672 ADAM10 82.63% 97.50%
CHEMBL3359 P21462 Formyl peptide receptor 1 82.11% 93.56%
CHEMBL255 P29275 Adenosine A2b receptor 81.84% 98.59%
CHEMBL2535 P11166 Glucose transporter 80.40% 98.75%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 13856319
LOTUS LTS0197372
wikiData Q77311045