Nigrospine

Details

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Internal ID 4e83a08c-9a34-438e-9304-989cfb182ff4
Taxonomy Organoheterocyclic compounds > Coumarans
IUPAC Name (3S,3aS,8bS)-3a,8,8b-trihydroxy-6-[(2S,3R)-3-hydroxybutan-2-yl]-3-[(1R)-1-hydroxyethyl]-2,7-dimethyl-3H-[1]benzofuro[2,3-c]pyrrol-1-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C18H25NO7/c1-7(9(3)20)11-6-12-13(14(22)8(11)2)17(24)16(23)19(5)15(10(4)21)18(17,25)26-12/h6-7,9-10,15,20-22,24-25H,1-5H3/t7-,9-,10-,15+,17-,18+/m1/s1
InChI Key JELWCSRCEBMYQY-NFCVBWQWSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C18H25NO7
Molecular Weight 367.40 g/mol
Exact Mass 367.16310214 g/mol
Topological Polar Surface Area (TPSA) 131.00 Ų
XlogP 0.10

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Nigrospine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 98.78% 98.95%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.17% 85.14%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 95.87% 93.40%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.72% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.21% 95.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 92.42% 90.71%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 90.55% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 89.44% 89.00%
CHEMBL2553 Q15418 Ribosomal protein S6 kinase alpha 1 87.21% 85.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 86.74% 94.45%
CHEMBL2563 Q9UQL6 Histone deacetylase 5 86.64% 89.67%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.87% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 84.61% 86.33%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 84.42% 93.65%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.47% 99.23%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 82.50% 100.00%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 81.57% 99.15%
CHEMBL3401 O75469 Pregnane X receptor 81.35% 94.73%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 81.03% 95.89%
CHEMBL3192 Q9BY41 Histone deacetylase 8 80.38% 93.99%
CHEMBL3359 P21462 Formyl peptide receptor 1 80.18% 93.56%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

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PubChem 139588196
LOTUS LTS0085253
wikiData Q105126195