Neoxaline

Details

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Internal ID d9ac362e-78e3-4033-a678-0c6a257f6c48
Taxonomy Organoheterocyclic compounds > Indoles and derivatives > Pyridoindoles > Pyridoindolones
IUPAC Name (14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C23H25N5O4/c1-5-21(2,3)22-11-18(29)20(31)27-17(10-14-12-24-13-25-14)19(30)26-23(22,27)28(32-4)16-9-7-6-8-15(16)22/h5-10,12-13,18,29H,1,11H2,2-4H3,(H,24,25)(H,26,30)/b17-10+
InChI Key HHLNXXASUKFCCX-LICLKQGHSA-N
Popularity 9 references in papers

Physical and Chemical Properties

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Molecular Formula C23H25N5O4
Molecular Weight 435.50 g/mol
Exact Mass 435.19065430 g/mol
Topological Polar Surface Area (TPSA) 111.00 Ų
XlogP 2.40

Synonyms

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71812-10-7
Nedoxaline
(14E)-11-hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione
(14Z)-11-Hydroxy-14-(1H-imidazol-5-ylmethylidene)-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.01,13.03,8]hexadeca-3,5,7-triene-12,15-dione
7a-(1,1-Dimethyl-2-propenyl)-6,7,7a,12-tetrahydro-6-hydroxy-3-(1H-imidazol-4-ylmethylene)-12-methoxy-1H,5H-imidazo[1',2'
BRN 5669473
SCHEMBL21194964
DTXSID80893992
HB3996
AKOS040753246
There are more than 10 synonyms. If you wish to see them all click here.

2D Structure

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2D Structure of Neoxaline

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.74% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 96.38% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 93.94% 95.56%
CHEMBL2581 P07339 Cathepsin D 92.18% 98.95%
CHEMBL2035 P08912 Muscarinic acetylcholine receptor M5 92.15% 94.62%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.45% 86.33%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 91.37% 93.03%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 90.02% 92.88%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 89.53% 91.07%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 88.94% 99.23%
CHEMBL1821 P08173 Muscarinic acetylcholine receptor M4 88.77% 94.08%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 87.75% 94.45%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.35% 95.89%
CHEMBL253 P34972 Cannabinoid CB2 receptor 86.77% 97.25%
CHEMBL1937 Q92769 Histone deacetylase 2 86.43% 94.75%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 85.91% 85.14%
CHEMBL2095226 P05556 Integrin alpha-5/beta-1 85.88% 96.39%
CHEMBL5409 Q8TDU6 G-protein coupled bile acid receptor 1 84.49% 93.65%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 83.80% 97.33%
CHEMBL2850 P49840 Glycogen synthase kinase-3 alpha 82.61% 88.84%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.58% 97.09%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.73% 94.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 6440491
LOTUS LTS0075480
wikiData Q15425784