Neonectriolide E

Details

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Internal ID 116ef23a-d84d-4a1b-bf1e-8f26a3aa3248
Taxonomy Organoheterocyclic compounds > Naphthopyrans
IUPAC Name (1S,2R,4R,6S)-14-hydroxy-10-methoxy-4,12-dimethyl-6-[[(2R)-5-oxooxolan-2-yl]methyl]-5,7,17-trioxapentacyclo[9.6.2.02,6.08,18.015,19]nonadeca-8,10,12,14,18-pentaen-16-one
SMILES (Canonical) CC1CC2C3C4=C5C(=C(C=C4OC2(O1)CC6CCC(=O)O6)OC)C(=CC(=C5C(=O)O3)O)C
SMILES (Isomeric) C[C@@H]1C[C@@H]2[C@H]3C4=C5C(=C(C=C4O[C@@]2(O1)C[C@H]6CCC(=O)O6)OC)C(=CC(=C5C(=O)O3)O)C
InChI InChI=1S/C24H24O8/c1-10-6-14(25)19-21-18(10)15(28-3)8-16-20(21)22(30-23(19)27)13-7-11(2)31-24(13,32-16)9-12-4-5-17(26)29-12/h6,8,11-13,22,25H,4-5,7,9H2,1-3H3/t11-,12-,13-,22+,24+/m1/s1
InChI Key ZALCZOUYJXZXGH-SDGSCWNDSA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C24H24O8
Molecular Weight 440.40 g/mol
Exact Mass 440.14711772 g/mol
Topological Polar Surface Area (TPSA) 101.00 Ų
XlogP 3.90

Synonyms

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CHEMBL3590129

2D Structure

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2D Structure of Neonectriolide E

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.41% 91.11%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.68% 85.14%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.05% 95.56%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.84% 96.09%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 93.25% 91.79%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.39% 97.09%
CHEMBL4208 P20618 Proteasome component C5 91.67% 90.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.47% 86.33%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 90.82% 94.00%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.75% 89.00%
CHEMBL241 Q14432 Phosphodiesterase 3A 90.49% 92.94%
CHEMBL2581 P07339 Cathepsin D 89.52% 98.95%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 89.20% 93.40%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.17% 99.23%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 88.79% 92.62%
CHEMBL5608 Q16288 NT-3 growth factor receptor 88.15% 95.89%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 87.93% 96.21%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 86.68% 82.38%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 86.15% 91.07%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 84.69% 97.14%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 83.56% 96.38%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 83.41% 90.24%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 82.67% 94.45%
CHEMBL3820 P35557 Hexokinase type IV 82.22% 91.96%
CHEMBL4581 P52732 Kinesin-like protein 1 81.92% 93.18%
CHEMBL1994 P08235 Mineralocorticoid receptor 80.47% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 122181370
LOTUS LTS0064580
wikiData Q105369926