Neoansamycin B

Details

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Internal ID c299f0e1-8477-4116-92df-09cc481ee787
Taxonomy Benzenoids > Tetralins
IUPAC Name (1S,3Z,8S,10S,11R,12S,15S)-4-ethyl-20-hydroxy-8-methoxy-10-methyl-12-pentyl-2-oxa-14-azahexacyclo[13.7.1.01,10.03,21.011,15.017,22]tricosa-3,17(22),18,20-tetraene-9,13,16-trione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C30H37NO6/c1-5-7-8-11-18-24-28(3)26(34)20(36-4)12-9-10-16(6-2)23-21-19(32)14-13-17-22(21)30(28,37-23)15-29(24,25(17)33)31-27(18)35/h13-14,18,20,24,32H,5-12,15H2,1-4H3,(H,31,35)/b23-16-/t18-,20-,24+,28+,29-,30-/m0/s1
InChI Key TVLUPXCVJZZKDZ-RENLGDBXSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C30H37NO6
Molecular Weight 507.60 g/mol
Exact Mass 507.26208790 g/mol
Topological Polar Surface Area (TPSA) 102.00 Ų
XlogP 4.00

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Neoansamycin B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.21% 98.95%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.04% 91.11%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 97.81% 96.38%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.05% 94.45%
CHEMBL3137262 O60341 LSD1/CoREST complex 96.76% 97.09%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.49% 96.09%
CHEMBL2996 Q05655 Protein kinase C delta 95.89% 97.79%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.97% 95.56%
CHEMBL1951 P21397 Monoamine oxidase A 93.20% 91.49%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 93.17% 92.88%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.60% 97.25%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.80% 93.56%
CHEMBL1907 P15144 Aminopeptidase N 91.31% 93.31%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.70% 99.23%
CHEMBL5608 Q16288 NT-3 growth factor receptor 90.20% 95.89%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 89.69% 92.62%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 88.33% 96.21%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 87.28% 100.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 87.25% 86.33%
CHEMBL230 P35354 Cyclooxygenase-2 86.86% 89.63%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.52% 93.03%
CHEMBL1994 P08235 Mineralocorticoid receptor 84.86% 100.00%
CHEMBL3401 O75469 Pregnane X receptor 82.77% 94.73%
CHEMBL3475 P05121 Plasminogen activator inhibitor-1 82.40% 83.00%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 81.88% 91.71%
CHEMBL3922 P50579 Methionine aminopeptidase 2 81.74% 97.28%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.65% 94.00%
CHEMBL5103 Q969S8 Histone deacetylase 10 80.62% 90.08%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139587102
LOTUS LTS0199536
wikiData Q77521477