Ncgc00385306-01_C21H23NO5_

Details

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Internal ID 2335f270-b7d4-4c3d-b02d-522d16a49e50
Taxonomy Organoheterocyclic compounds > Benzazepines
IUPAC Name 12,16-dimethoxy-21-methyl-4,6-dioxa-21-azapentacyclo[10.9.0.02,10.03,7.013,18]henicosa-2(10),3(7),8,13,15,17-hexaen-15-ol
SMILES (Canonical) CN1CCC2=CC(=C(C=C2C3(C1C4=C(C3)C=CC5=C4OCO5)OC)O)OC
SMILES (Isomeric) CN1CCC2=CC(=C(C=C2C3(C1C4=C(C3)C=CC5=C4OCO5)OC)O)OC
InChI InChI=1S/C21H23NO5/c1-22-7-6-12-8-17(24-2)15(23)9-14(12)21(25-3)10-13-4-5-16-19(27-11-26-16)18(13)20(21)22/h4-5,8-9,20,23H,6-7,10-11H2,1-3H3
InChI Key UVACAWVKXUAPRQ-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C21H23NO5
Molecular Weight 369.40 g/mol
Exact Mass 369.15762283 g/mol
Topological Polar Surface Area (TPSA) 60.40 Ų
XlogP 2.50

Synonyms

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NCGC00385306-01_C21H23NO5_

2D Structure

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2D Structure of Ncgc00385306-01_C21H23NO5_

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.01% 96.09%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.30% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.55% 95.56%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 94.96% 96.77%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 93.52% 93.40%
CHEMBL2581 P07339 Cathepsin D 92.31% 98.95%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 91.76% 92.62%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.52% 85.14%
CHEMBL3192 Q9BY41 Histone deacetylase 8 90.67% 93.99%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 90.26% 94.00%
CHEMBL1293249 Q13887 Kruppel-like factor 5 89.29% 86.33%
CHEMBL5608 Q16288 NT-3 growth factor receptor 89.15% 95.89%
CHEMBL4208 P20618 Proteasome component C5 88.96% 90.00%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 88.66% 82.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.39% 94.45%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 87.92% 89.62%
CHEMBL2056 P21728 Dopamine D1 receptor 86.47% 91.00%
CHEMBL2413 P32246 C-C chemokine receptor type 1 84.40% 89.50%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 84.01% 82.38%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.79% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.33% 89.00%
CHEMBL1951 P21397 Monoamine oxidase A 83.00% 91.49%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 82.99% 100.00%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 81.67% 90.95%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 81.21% 91.79%
CHEMBL5339 Q5NUL3 G-protein coupled receptor 120 80.44% 95.78%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 80.28% 99.15%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Fumaria densiflora
Fumaria rostellata

Cross-Links

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PubChem 75528888
LOTUS LTS0057270
wikiData Q105279703