Naquihexcin H

Details

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Internal ID 0ae0b897-5c0a-4e1f-bf68-3b077e81ec6b
Taxonomy Organoheterocyclic compounds > Naphthopyrans > Naphthopyranones > Naphthopyranone glycosides
IUPAC Name (2R,3R,4R,5S,6R)-6-[[(1S,3S,4aS,10aR)-4a-[[(1S,3S,4aS,10aR)-9,10a-dihydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-4a-yl]sulfanyl]-9,10a-dihydroxy-3-(2-methoxy-2-oxoethyl)-1-methyl-5,10-dioxo-3,4-dihydro-1H-benzo[g]isochromen-8-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C40H42O21S/c1-14-39(54)33(50)24-18(6-5-7-20(24)41)31(48)37(39,12-16(58-14)10-22(42)56-3)62-38-13-17(11-23(43)57-4)59-15(2)40(38,55)34(51)25-19(32(38)49)8-9-21(26(25)44)60-36-29(47)27(45)28(46)30(61-36)35(52)53/h5-9,14-17,27-30,36,41,44-47,54-55H,10-13H2,1-4H3,(H,52,53)/t14-,15-,16-,17-,27+,28+,29-,30+,36-,37+,38+,39+,40+/m0/s1
InChI Key YKYYSFPTRCUBFI-MTMWHFOQSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C40H42O21S
Molecular Weight 890.80 g/mol
Exact Mass 890.19392952 g/mol
Topological Polar Surface Area (TPSA) 362.00 Ų
XlogP 0.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Naquihexcin H

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL1951 P21397 Monoamine oxidase A 99.10% 91.49%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.85% 91.11%
CHEMBL2581 P07339 Cathepsin D 98.64% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 96.43% 95.56%
CHEMBL1293249 Q13887 Kruppel-like factor 5 94.30% 86.33%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 93.90% 96.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 93.27% 95.89%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.16% 89.00%
CHEMBL4208 P20618 Proteasome component C5 88.63% 90.00%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.94% 97.14%
CHEMBL1255126 O15151 Protein Mdm4 84.33% 90.20%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.38% 91.07%
CHEMBL1994 P08235 Mineralocorticoid receptor 83.29% 100.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 82.98% 96.90%
CHEMBL5028 O14672 ADAM10 82.93% 97.50%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.46% 97.09%
CHEMBL2535 P11166 Glucose transporter 81.91% 98.75%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 81.81% 99.23%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 80.76% 94.00%
CHEMBL3492 P49721 Proteasome Macropain subunit 80.71% 90.24%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.69% 99.17%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 80.53% 85.14%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 80.32% 96.00%
CHEMBL340 P08684 Cytochrome P450 3A4 80.23% 91.19%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 145721039
LOTUS LTS0098198
wikiData Q105349979