Naphthgeranine B

Details

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Internal ID adb01e1a-28eb-4ac7-a04a-363ac3f2fe4e
Taxonomy Organoheterocyclic compounds > Naphthopyrans > Naphthopyranones
IUPAC Name (4aS,12bR)-8,10-dihydroxy-2-(hydroxymethyl)-5,5-dimethyl-3,4,4a,12b-tetrahydronaphtho[2,3-c]isochromene-7,12-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C20H20O6/c1-20(2)13-4-3-9(8-21)5-11(13)16-17(24)12-6-10(22)7-14(23)15(12)18(25)19(16)26-20/h5-7,11,13,21-23H,3-4,8H2,1-2H3/t11-,13+/m1/s1
InChI Key PTWDQKQKJHACJW-YPMHNXCESA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C20H20O6
Molecular Weight 356.40 g/mol
Exact Mass 356.12598835 g/mol
Topological Polar Surface Area (TPSA) 104.00 Ų
XlogP 2.10

Synonyms

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137109-44-5
(4aS,12bR)-8,10-dihydroxy-2-(hydroxymethyl)-5,5-dimethyl-3,4,4a,12b-tetrahydronaphtho[2,3-c]isochromene-7,12-dione
DTXSID20160079
4H-Benzo(d)naphtho(2,3-b)pyran-7,12-dione, 3,4a,5,12b-tetrahydro-8,10-dihydroxy-2-(hydroxymethyl)-5,5-dimethyl-, (4aS-cis)-

2D Structure

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2D Structure of Naphthgeranine B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.73% 91.11%
CHEMBL2581 P07339 Cathepsin D 96.45% 98.95%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 94.96% 96.38%
CHEMBL226 P30542 Adenosine A1 receptor 94.39% 95.93%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.24% 96.09%
CHEMBL1806 P11388 DNA topoisomerase II alpha 94.19% 89.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.04% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 91.66% 99.23%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 91.43% 94.45%
CHEMBL1994 P08235 Mineralocorticoid receptor 91.09% 100.00%
CHEMBL1929 P47989 Xanthine dehydrogenase 90.65% 96.12%
CHEMBL4208 P20618 Proteasome component C5 87.99% 90.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.36% 97.09%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 85.79% 93.40%
CHEMBL3192 Q9BY41 Histone deacetylase 8 84.03% 93.99%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.64% 94.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 83.62% 95.89%
CHEMBL3038469 P24941 CDK2/Cyclin A 83.61% 91.38%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 83.27% 96.21%
CHEMBL1937 Q92769 Histone deacetylase 2 81.48% 94.75%
CHEMBL3401 O75469 Pregnane X receptor 81.19% 94.73%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.11% 93.03%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 80.68% 90.71%
CHEMBL4940 P07195 L-lactate dehydrogenase B chain 80.60% 95.53%
CHEMBL1951 P21397 Monoamine oxidase A 80.58% 91.49%
CHEMBL2964 P36507 Dual specificity mitogen-activated protein kinase kinase 2 80.11% 80.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132026
LOTUS LTS0054846
wikiData Q83028461