LP2006

Details

Top
Internal ID 018a218a-15f9-41b0-a410-c477cb31ce6e
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name (4R,7S,10S,13S,16R)-16-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(3S,11S,14S,20S,23S,26S)-23-(2-amino-2-oxoethyl)-14-benzyl-3-(3-carbamimidamidopropyl)-20-(1H-indol-3-ylmethyl)-2,5,8,13,16,19,22,25-octaoxo-1,4,7,12,15,18,21,24-octazabicyclo[24.3.0]nonacosane-11-carbonyl]amino]-4-oxobutanoyl]amino]-3-carboxypropanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-10-(3-carbamimidamidopropyl)-6,9,12,15-tetraoxo-7,13-di(propan-2-yl)-1,2-dithia-5,8,11,14-tetrazacycloheptadecane-4-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C88H121N27O24S2/c1-42(2)70-83(135)104-51(21-12-26-95-87(91)92)74(126)113-71(43(3)4)84(136)112-62(86(138)139)41-141-140-40-61(81(133)114-70)111-80(132)60(39-116)110-76(128)56(31-46-36-98-50-20-11-9-18-48(46)50)106-79(131)59(34-69(122)123)108-77(129)57(32-64(89)117)107-73(125)52-24-25-66(119)99-37-67(120)101-53(22-13-27-96-88(93)94)85(137)115-28-14-23-63(115)82(134)109-58(33-65(90)118)78(130)105-55(30-45-35-97-49-19-10-8-17-47(45)49)72(124)100-38-68(121)102-54(75(127)103-52)29-44-15-6-5-7-16-44/h5-11,15-20,35-36,42-43,51-63,70-71,97-98,116H,12-14,21-34,37-41H2,1-4H3,(H2,89,117)(H2,90,118)(H,99,119)(H,100,124)(H,101,120)(H,102,121)(H,103,127)(H,104,135)(H,105,130)(H,106,131)(H,107,125)(H,108,129)(H,109,134)(H,110,128)(H,111,132)(H,112,136)(H,113,126)(H,114,133)(H,122,123)(H,138,139)(H4,91,92,95)(H4,93,94,96)/t51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,70-,71-/m0/s1
InChI Key DGLXWTNAXWDXII-QUIRKDHJSA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C88H121N27O24S2
Molecular Weight 2005.20 g/mol
Exact Mass 2003.8519202 g/mol
Topological Polar Surface Area (TPSA) 873.00 Ų
XlogP -4.70

Synonyms

Top
There are no found synonyms.

2D Structure

Top
2D Structure of LP2006

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.97% 98.95%
CHEMBL4040 P28482 MAP kinase ERK2 99.92% 83.82%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.83% 96.09%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 99.64% 97.64%
CHEMBL1914 P06276 Butyrylcholinesterase 99.44% 95.00%
CHEMBL333 P08253 Matrix metalloproteinase-2 99.16% 96.31%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.73% 91.11%
CHEMBL5103 Q969S8 Histone deacetylase 10 98.50% 90.08%
CHEMBL261 P00915 Carbonic anhydrase I 98.40% 96.76%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.36% 94.45%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 98.11% 91.81%
CHEMBL3310 Q96DB2 Histone deacetylase 11 97.99% 88.56%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 97.72% 95.00%
CHEMBL4296 Q15858 Sodium channel protein type IX alpha subunit 97.65% 96.11%
CHEMBL4462 Q8IXJ6 NAD-dependent deacetylase sirtuin 2 97.35% 90.24%
CHEMBL3837 P07711 Cathepsin L 97.19% 96.61%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 96.65% 85.14%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 96.65% 98.33%
CHEMBL2821 P00748 Coagulation factor XII 96.58% 96.21%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 96.02% 97.14%
CHEMBL4588 P22894 Matrix metalloproteinase 8 96.00% 94.66%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 95.80% 93.10%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 95.64% 96.90%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 95.54% 96.67%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.37% 95.56%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 94.76% 88.42%
CHEMBL1801 P00747 Plasminogen 94.72% 92.44%
CHEMBL4071 P08311 Cathepsin G 94.65% 94.64%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 94.20% 97.23%
CHEMBL2093869 P05106 Integrin alpha-IIb/beta-3 94.14% 95.42%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 93.93% 95.50%
CHEMBL3468 P55210 Caspase-7 93.89% 95.68%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 93.62% 91.71%
CHEMBL3524 P56524 Histone deacetylase 4 93.41% 92.97%
CHEMBL1293287 P14735 Insulin-degrading enzyme 93.39% 88.10%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 93.16% 95.83%
CHEMBL5608 Q16288 NT-3 growth factor receptor 92.56% 95.89%
CHEMBL221 P23219 Cyclooxygenase-1 92.10% 90.17%
CHEMBL259 P32245 Melanocortin receptor 4 91.60% 95.38%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 91.42% 99.09%
CHEMBL321 P14780 Matrix metalloproteinase 9 91.42% 92.12%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 91.36% 98.24%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 91.19% 93.00%
CHEMBL255 P29275 Adenosine A2b receptor 90.72% 98.59%
CHEMBL1075317 P61964 WD repeat-containing protein 5 90.63% 96.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.17% 97.09%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 89.89% 82.38%
CHEMBL1255126 O15151 Protein Mdm4 89.64% 90.20%
CHEMBL5261 Q7L7X3 Serine/threonine-protein kinase TAO1 89.34% 89.33%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 88.98% 96.03%
CHEMBL4801 P29466 Caspase-1 88.87% 96.85%
CHEMBL3729 P22748 Carbonic anhydrase IV 88.60% 99.23%
CHEMBL1628481 P35414 Apelin receptor 88.30% 97.89%
CHEMBL5028 O14672 ADAM10 88.00% 97.50%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 87.62% 83.10%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 87.57% 90.93%
CHEMBL5805 Q9NR97 Toll-like receptor 8 87.36% 96.25%
CHEMBL1744525 P43490 Nicotinamide phosphoribosyltransferase 86.95% 96.25%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.71% 99.23%
CHEMBL213 P08588 Beta-1 adrenergic receptor 86.29% 95.56%
CHEMBL340 P08684 Cytochrome P450 3A4 86.17% 91.19%
CHEMBL5701 Q9H2K8 Serine/threonine-protein kinase TAO3 86.12% 96.67%
CHEMBL2072 P35499 Sodium channel protein type IV alpha subunit 85.82% 92.32%
CHEMBL2514 O95665 Neurotensin receptor 2 85.79% 100.00%
CHEMBL2535 P11166 Glucose transporter 85.55% 98.75%
CHEMBL220 P22303 Acetylcholinesterase 85.38% 94.45%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 85.29% 93.03%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 85.09% 96.47%
CHEMBL4018 P49146 Neuropeptide Y receptor type 2 85.05% 98.94%
CHEMBL3024 P53350 Serine/threonine-protein kinase PLK1 85.00% 97.43%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 84.33% 97.33%
CHEMBL3155 P34969 Serotonin 7 (5-HT7) receptor 84.29% 90.71%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 83.89% 100.00%
CHEMBL3384 Q16512 Protein kinase N1 83.40% 80.71%
CHEMBL1806 P11388 DNA topoisomerase II alpha 83.30% 89.00%
CHEMBL1781 P11387 DNA topoisomerase I 83.09% 97.00%
CHEMBL1980 Q14524 Sodium channel protein type V alpha subunit 83.05% 92.50%
CHEMBL2094135 Q96BI3 Gamma-secretase 82.92% 98.05%
CHEMBL3091268 Q92753 Nuclear receptor ROR-beta 82.67% 95.50%
CHEMBL3176 O43603 Galanin receptor 2 82.19% 98.89%
CHEMBL3060 Q9Y345 Glycine transporter 2 81.88% 99.17%
CHEMBL2068 P29317 Ephrin type-A receptor 2 81.64% 97.49%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 81.60% 85.00%
CHEMBL4330 Q9NS75 Cysteinyl leukotriene receptor 2 81.11% 98.00%
CHEMBL3202 P48147 Prolyl endopeptidase 81.04% 90.65%
CHEMBL4302 P08183 P-glycoprotein 1 80.58% 92.98%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 124080863
LOTUS LTS0084957
wikiData Q104978883