Colibactin prodrug motif

Details

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Internal ID b5cb6e35-9e7a-422c-a65f-2373d412c241
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Asparagine and derivatives
IUPAC Name (2R)-4-amino-4-oxo-2-(tetradecanoylamino)butanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C18H34N2O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-17(22)20-15(18(23)24)14-16(19)21/h15H,2-14H2,1H3,(H2,19,21)(H,20,22)(H,23,24)/t15-/m1/s1
InChI Key XCYGCBVZSVXYON-OAHLLOKOSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C18H34N2O4
Molecular Weight 342.50 g/mol
Exact Mass 342.25185757 g/mol
Topological Polar Surface Area (TPSA) 109.00 Ų
XlogP 4.30

Synonyms

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SCHEMBL21724437

2D Structure

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2D Structure of Colibactin prodrug motif

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3060 Q9Y345 Glycine transporter 2 98.53% 99.17%
CHEMBL2581 P07339 Cathepsin D 97.91% 98.95%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 95.31% 95.17%
CHEMBL4040 P28482 MAP kinase ERK2 95.29% 83.82%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 94.28% 92.08%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.07% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 93.89% 90.17%
CHEMBL230 P35354 Cyclooxygenase-2 92.41% 89.63%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 91.56% 97.29%
CHEMBL3359 P21462 Formyl peptide receptor 1 90.10% 93.56%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 90.02% 96.95%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 88.95% 100.00%
CHEMBL2001 Q9H244 Purinergic receptor P2Y12 88.73% 96.00%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.53% 91.11%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 88.25% 91.81%
CHEMBL1255126 O15151 Protein Mdm4 87.37% 90.20%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 86.36% 92.29%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 85.72% 97.21%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 85.02% 96.47%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 83.83% 90.71%
CHEMBL340 P08684 Cytochrome P450 3A4 82.31% 91.19%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 81.46% 96.00%
CHEMBL2955 O95136 Sphingosine 1-phosphate receptor Edg-5 81.28% 92.86%
CHEMBL5255 O00206 Toll-like receptor 4 80.46% 92.50%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 80.08% 93.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 102500690
LOTUS LTS0073009
wikiData Q105325546