N-Methylsinactine

Details

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Internal ID a7a74cad-7317-49f2-b7d4-0d208e5f5d97
Taxonomy Alkaloids and derivatives > Protoberberine alkaloids and derivatives
IUPAC Name (1S,13S)-16,17-dimethoxy-1-methyl-5,7-dioxa-1-azoniapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),9,14,16,18-hexaene
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H24NO4/c1-22-7-6-14-9-19(23-2)20(24-3)10-15(14)17(22)8-13-4-5-18-21(16(13)11-22)26-12-25-18/h4-5,9-10,17H,6-8,11-12H2,1-3H3/q+1/t17-,22-/m0/s1
InChI Key MTDQIOGTAVVTIY-JTSKRJEESA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H24NO4+
Molecular Weight 354.40 g/mol
Exact Mass 354.17053325 g/mol
Topological Polar Surface Area (TPSA) 36.90 Ų
XlogP 3.10

Synonyms

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(S)-cis-N-Methylsinactine

2D Structure

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2D Structure of N-Methylsinactine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL261 P00915 Carbonic anhydrase I 96.84% 96.76%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.29% 96.09%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 94.10% 82.67%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.06% 94.45%
CHEMBL241 Q14432 Phosphodiesterase 3A 93.69% 92.94%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.20% 91.11%
CHEMBL3192 Q9BY41 Histone deacetylase 8 92.08% 93.99%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 91.80% 93.40%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 91.70% 96.77%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.93% 86.33%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 90.85% 92.62%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.37% 95.56%
CHEMBL2535 P11166 Glucose transporter 90.32% 98.75%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 89.23% 91.79%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.29% 95.89%
CHEMBL4247 Q9UM73 ALK tyrosine kinase receptor 84.82% 96.86%
CHEMBL5896 O75164 Lysine-specific demethylase 4A 84.42% 99.09%
CHEMBL2581 P07339 Cathepsin D 84.35% 98.95%
CHEMBL2413 P32246 C-C chemokine receptor type 1 83.37% 89.50%
CHEMBL5747 Q92793 CREB-binding protein 83.01% 95.12%
CHEMBL225 P28335 Serotonin 2c (5-HT2c) receptor 82.75% 89.62%
CHEMBL4895 P30530 Tyrosine-protein kinase receptor UFO 82.53% 90.95%
CHEMBL3438 Q05513 Protein kinase C zeta 82.39% 88.48%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.71% 100.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 81.70% 96.00%
CHEMBL3137262 O60341 LSD1/CoREST complex 80.63% 97.09%
CHEMBL4681 P42330 Aldo-keto-reductase family 1 member C3 80.12% 89.05%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Fumaria officinalis

Cross-Links

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PubChem 163184404
LOTUS LTS0078480
wikiData Q105171641