Adametizine A

Details

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Internal ID 57084252-d020-40fb-8124-1aff50b2da1e
Taxonomy Benzenoids > Phenols > Methoxyphenols
IUPAC Name (1R,3R,4R,7R,8S,12S,13R)-4-chloro-3,7-dihydroxy-13-(2-hydroxy-3,4-dimethoxyphenyl)-17-methyl-9-oxa-14,15-dithia-10,17-diazatetracyclo[10.3.2.01,10.03,8]heptadec-5-ene-11,16-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H23ClN2O8S2/c1-23-13-16(9-4-6-11(30-2)15(31-3)14(9)26)33-34-21(19(23)28)8-20(29)12(22)7-5-10(25)17(20)32-24(21)18(13)27/h4-7,10,12-13,16-17,25-26,29H,8H2,1-3H3/t10-,12-,13-,16-,17+,20+,21-/m1/s1
InChI Key AWPMMJDFXQCEES-BFBGDVCSSA-N
Popularity 6 references in papers

Physical and Chemical Properties

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Molecular Formula C21H23ClN2O8S2
Molecular Weight 531.00 g/mol
Exact Mass 530.0584357 g/mol
Topological Polar Surface Area (TPSA) 180.00 Ų
XlogP 0.30

Synonyms

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CHEMBL4073822

2D Structure

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2D Structure of Adametizine A

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.23% 96.09%
CHEMBL2581 P07339 Cathepsin D 95.88% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.25% 95.56%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 90.88% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 90.79% 94.45%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 90.49% 96.77%
CHEMBL1293249 Q13887 Kruppel-like factor 5 90.06% 86.33%
CHEMBL5697 Q9GZT9 Egl nine homolog 1 89.73% 93.40%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 89.66% 94.00%
CHEMBL3192 Q9BY41 Histone deacetylase 8 86.27% 93.99%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.83% 95.89%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.32% 97.25%
CHEMBL1806 P11388 DNA topoisomerase II alpha 85.26% 89.00%
CHEMBL4208 P20618 Proteasome component C5 83.86% 90.00%
CHEMBL217 P14416 Dopamine D2 receptor 83.16% 95.62%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 82.83% 99.23%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 82.19% 97.33%
CHEMBL2085 P14174 Macrophage migration inhibitory factor 80.88% 80.78%
CHEMBL2056 P21728 Dopamine D1 receptor 80.83% 91.00%
CHEMBL2335 P42785 Lysosomal Pro-X carboxypeptidase 80.77% 100.00%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 80.76% 82.38%
CHEMBL4829 O00763 Acetyl-CoA carboxylase 2 80.57% 98.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 132552383
LOTUS LTS0070578
wikiData Q77505400