N-L-alanyl-3-(((3-(aminocarbonyl)oxiranyl)carbonyl)amino)-L-alanine

Details

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Internal ID afecaadd-8ad2-4d7e-8873-792b7b044c1f
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > Alanine and derivatives
IUPAC Name [(2S)-2-aminopropanoyl] (2S)-2-amino-3-[[(2R,3R)-3-carbamoyloxirane-2-carbonyl]amino]propanoate
SMILES (Canonical) CC(C(=O)OC(=O)C(CNC(=O)C1C(O1)C(=O)N)N)N
SMILES (Isomeric) C[C@@H](C(=O)OC(=O)[C@H](CNC(=O)[C@H]1[C@@H](O1)C(=O)N)N)N
InChI InChI=1S/C10H16N4O6/c1-3(11)9(17)20-10(18)4(12)2-14-8(16)6-5(19-6)7(13)15/h3-6H,2,11-12H2,1H3,(H2,13,15)(H,14,16)/t3-,4-,5+,6+/m0/s1
InChI Key ZJOXNGKKGAAFJU-UNTFVMJOSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C10H16N4O6
Molecular Weight 288.26 g/mol
Exact Mass 288.10698424 g/mol
Topological Polar Surface Area (TPSA) 180.00 Ų
XlogP -3.50

Synonyms

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[(2S)-2-aminopropanoyl] (2S)-2-amino-3-[[(2R,3R)-3-carbamoyloxirane-2-carbonyl]amino]propanoate
Sch-37137
L-Alanine, N-L-alanyl-3-(((3-(aminocarbonyl)oxiranyl)carbonyl)amino)-

2D Structure

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2D Structure of N-L-alanyl-3-(((3-(aminocarbonyl)oxiranyl)carbonyl)amino)-L-alanine

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.73% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 95.52% 83.82%
CHEMBL4657 Q6V1X1 Dipeptidyl peptidase VIII 94.20% 97.21%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 93.82% 96.95%
CHEMBL3437 Q16853 Amine oxidase, copper containing 92.92% 94.00%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 92.26% 92.29%
CHEMBL253 P34972 Cannabinoid CB2 receptor 90.85% 97.25%
CHEMBL3830 Q2M2I8 Adaptor-associated kinase 89.99% 83.10%
CHEMBL2730 P21980 Protein-glutamine gamma-glutamyltransferase 89.27% 92.38%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.70% 91.11%
CHEMBL255 P29275 Adenosine A2b receptor 88.32% 98.59%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.01% 99.17%
CHEMBL2581 P07339 Cathepsin D 85.70% 98.95%
CHEMBL2179 P04062 Beta-glucocerebrosidase 85.35% 85.31%
CHEMBL226 P30542 Adenosine A1 receptor 85.30% 95.93%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 85.22% 94.33%
CHEMBL1293267 Q9HC97 G-protein coupled receptor 35 84.91% 89.34%
CHEMBL236 P41143 Delta opioid receptor 84.64% 99.35%
CHEMBL3137262 O60341 LSD1/CoREST complex 82.97% 97.09%
CHEMBL3401 O75469 Pregnane X receptor 82.70% 94.73%
CHEMBL340 P08684 Cytochrome P450 3A4 82.15% 91.19%
CHEMBL2413 P32246 C-C chemokine receptor type 1 81.72% 89.50%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 81.66% 96.47%
CHEMBL4227 P25090 Lipoxin A4 receptor 81.09% 100.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 197244
LOTUS LTS0212753
wikiData Q76084778