N-hydroxy-L-arginine (NOHA)

Details

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Internal ID 67d62703-684d-4dfd-9828-00c38417956d
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Alpha amino acids and derivatives > N-hydroxyl-alpha-amino acids
IUPAC Name (2S)-5-(diaminomethylideneamino)-2-(hydroxyamino)pentanoic acid
SMILES (Canonical) C(CC(C(=O)O)NO)CN=C(N)N
SMILES (Isomeric) C(C[C@@H](C(=O)O)NO)CN=C(N)N
InChI InChI=1S/C6H14N4O3/c7-6(8)9-3-1-2-4(10-13)5(11)12/h4,10,13H,1-3H2,(H,11,12)(H4,7,8,9)/t4-/m0/s1
InChI Key WQFIAVZQVYASHZ-BYPYZUCNSA-N
Popularity 213 references in papers

Physical and Chemical Properties

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Molecular Formula C6H14N4O3
Molecular Weight 190.20 g/mol
Exact Mass 190.10659032 g/mol
Topological Polar Surface Area (TPSA) 134.00 Ų
XlogP -4.20

Synonyms

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N-hydroxy-L-arginine (NOHA)
BDBM130379

2D Structure

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2D Structure of N-hydroxy-L-arginine (NOHA)

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3060 Q9Y345 Glycine transporter 2 93.77% 99.17%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.50% 96.09%
CHEMBL221 P23219 Cyclooxygenase-1 90.87% 90.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 89.97% 91.11%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 88.55% 96.00%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 88.33% 100.00%
CHEMBL4040 P28482 MAP kinase ERK2 87.76% 83.82%
CHEMBL2581 P07339 Cathepsin D 84.82% 98.95%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 84.69% 90.71%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 84.67% 94.45%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 84.11% 97.29%
CHEMBL2514 O95665 Neurotensin receptor 2 83.81% 100.00%
CHEMBL1255126 O15151 Protein Mdm4 82.98% 90.20%
CHEMBL204 P00734 Thrombin 81.91% 96.01%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 81.60% 92.29%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 81.44% 95.17%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 80.23% 96.47%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Cycas revoluta

Cross-Links

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PubChem 9836994
LOTUS LTS0106777
wikiData Q105310688