Mycalamide A

Details

Top
Internal ID e357d0db-1d0e-4e6a-a254-94d68b304b5e
Taxonomy Organoheterocyclic compounds > Pyranodioxins
IUPAC Name (2S)-N-[(4S,4aS,6R,8S,8aR)-6-[(2S)-2,3-dihydroxypropyl]-8-methoxy-7,7-dimethyl-4a,6,8,8a-tetrahydro-4H-pyrano[3,2-d][1,3]dioxin-4-yl]-2-hydroxy-2-[(2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C24H41NO10/c1-12-9-24(31-7,35-14(3)13(12)2)19(28)21(29)25-22-18-17(32-11-33-22)20(30-6)23(4,5)16(34-18)8-15(27)10-26/h13-20,22,26-28H,1,8-11H2,2-7H3,(H,25,29)/t13-,14-,15+,16-,17+,18+,19-,20-,22+,24-/m1/s1
InChI Key IJASURGZDJYQGF-GBNRTHSESA-N
Popularity 34 references in papers

Physical and Chemical Properties

Top
Molecular Formula C24H41NO10
Molecular Weight 503.60 g/mol
Exact Mass 503.27304650 g/mol
Topological Polar Surface Area (TPSA) 145.00 Ų
XlogP -0.10

Synonyms

Top
SCHEMBL598454
CHEMBL497451
DTXSID501317970
(2S)-N-[(4S,4aS,6R,8S,8aR)-6-[(2S)-2,3-dihydroxypropyl]-8-methoxy-7,7-dimethyl-4a,6,8,8a-tetrahydro-4H-pyrano[3,2-d][1,3]dioxin-4-yl]-2-hydroxy-2-[(2R,5R,6R)-2-methoxy-5,6-dimethyl-4-methylideneoxan-2-yl]acetamide

2D Structure

Top
2D Structure of Mycalamide A

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 98.76% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.48% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 95.75% 94.45%
CHEMBL1907602 P06493 Cyclin-dependent kinase 1/cyclin B1 93.61% 91.24%
CHEMBL1907605 P24864 Cyclin-dependent kinase 2/cyclin E1 92.24% 92.88%
CHEMBL2581 P07339 Cathepsin D 91.69% 98.95%
CHEMBL340 P08684 Cytochrome P450 3A4 90.68% 91.19%
CHEMBL3145 P42338 PI3-kinase p110-beta subunit 87.96% 98.75%
CHEMBL3401 O75469 Pregnane X receptor 87.09% 94.73%
CHEMBL253 P34972 Cannabinoid CB2 receptor 85.80% 97.25%
CHEMBL3060 Q9Y345 Glycine transporter 2 85.49% 99.17%
CHEMBL4051 P13569 Cystic fibrosis transmembrane conductance regulator 85.18% 95.71%
CHEMBL3267 P48736 PI3-kinase p110-gamma subunit 84.05% 95.71%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 83.69% 95.83%
CHEMBL4303 P08238 Heat shock protein HSP 90-beta 83.34% 96.77%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 83.29% 94.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.10% 97.09%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 82.51% 92.62%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 82.40% 96.47%
CHEMBL1293249 Q13887 Kruppel-like factor 5 81.25% 86.33%
CHEMBL218 P21554 Cannabinoid CB1 receptor 80.90% 96.61%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 80.82% 97.14%
CHEMBL2534 O15530 3-phosphoinositide dependent protein kinase-1 80.33% 95.36%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 80.24% 91.07%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 80.02% 95.50%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
There are no matching plants.

Cross-Links

Top
PubChem 10345974
LOTUS LTS0033380
wikiData Q105113870