Muraymycin B3

Details

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Internal ID 7dbdd88a-7ead-4a34-bb89-dbc81b766bd9
Taxonomy Organic acids and derivatives > Carboxylic acids and derivatives > Amino acids, peptides, and analogues > Peptides > Dipeptides
IUPAC Name (2S)-2-[[(1S)-2-[[(2S,3S)-1-[3-[[(1S,2S)-2-[(2S,3R,4R,5R)-5-(aminomethyl)-4-hydroxy-3-methoxyoxolan-2-yl]oxy-1-carboxy-2-[(2S,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]ethyl]amino]propylamino]-4-methyl-3-(6-methyloctanoyloxy)-1-oxopentan-2-yl]amino]-1-[(6S)-2-amino-1,4,5,6-tetrahydropyrimidin-6-yl]-2-oxoethyl]carbamoylamino]-3-methylbutanoic acid
SMILES (Canonical) CCC(C)CCCCC(=O)OC(C(C)C)C(C(=O)NCCCNC(C(C1C(C(C(O1)N2C=CC(=O)NC2=O)O)O)OC3C(C(C(O3)CN)O)OC)C(=O)O)NC(=O)C(C4CCN=C(N4)N)NC(=O)NC(C(C)C)C(=O)O
SMILES (Isomeric) CCC(C)CCCCC(=O)O[C@H]([C@@H](C(=O)NCCCN[C@@H]([C@@H]([C@@H]1[C@H]([C@H]([C@@H](O1)N2C=CC(=O)NC2=O)O)O)O[C@H]3[C@@H]([C@@H]([C@H](O3)CN)O)OC)C(=O)O)NC(=O)[C@H]([C@@H]4CCN=C(N4)N)NC(=O)N[C@@H](C(C)C)C(=O)O)C(C)C
InChI InChI=1S/C47H79N11O18/c1-8-23(6)12-9-10-13-27(60)74-35(22(4)5)30(55-40(65)29(24-14-18-52-45(49)53-24)57-46(70)56-28(21(2)3)42(66)67)39(64)51-17-11-16-50-31(43(68)69)36(76-44-38(72-7)32(61)25(20-48)73-44)37-33(62)34(63)41(75-37)58-19-15-26(59)54-47(58)71/h15,19,21-25,28-38,41,44,50,61-63H,8-14,16-18,20,48H2,1-7H3,(H,51,64)(H,55,65)(H,66,67)(H,68,69)(H3,49,52,53)(H,54,59,71)(H2,56,57,70)/t23?,24-,25+,28-,29-,30-,31-,32+,33-,34+,35-,36-,37-,38+,41+,44-/m0/s1
InChI Key MWCSUZGMQHRXMO-WDXBTKRESA-N
Popularity 1 reference in papers

Physical and Chemical Properties

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Molecular Formula C47H79N11O18
Molecular Weight 1086.20 g/mol
Exact Mass 1085.56045471 g/mol
Topological Polar Surface Area (TPSA) 436.00 Ų
XlogP -6.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Muraymycin B3

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.90% 98.95%
CHEMBL220 P22303 Acetylcholinesterase 99.83% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.72% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 96.56% 94.45%
CHEMBL3060 Q9Y345 Glycine transporter 2 95.91% 99.17%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 95.43% 91.11%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 94.50% 90.71%
CHEMBL255 P29275 Adenosine A2b receptor 93.18% 98.59%
CHEMBL4588 P22894 Matrix metalloproteinase 8 92.97% 94.66%
CHEMBL3137262 O60341 LSD1/CoREST complex 92.88% 97.09%
CHEMBL4227 P25090 Lipoxin A4 receptor 92.38% 100.00%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 91.87% 98.33%
CHEMBL3359 P21462 Formyl peptide receptor 1 91.79% 93.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.90% 99.23%
CHEMBL5028 O14672 ADAM10 90.71% 97.50%
CHEMBL5103 Q969S8 Histone deacetylase 10 90.19% 90.08%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 89.28% 95.00%
CHEMBL3401 O75469 Pregnane X receptor 88.72% 94.73%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.65% 95.89%
CHEMBL5255 O00206 Toll-like receptor 4 87.59% 92.50%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 87.14% 95.89%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 87.03% 93.00%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 86.59% 96.90%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 84.94% 94.33%
CHEMBL1075094 Q16236 Nuclear factor erythroid 2-related factor 2 84.13% 96.00%
CHEMBL226 P30542 Adenosine A1 receptor 83.89% 95.93%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 83.01% 100.00%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 83.00% 95.56%
CHEMBL204 P00734 Thrombin 82.18% 96.01%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 82.12% 97.50%
CHEMBL2492 P36544 Neuronal acetylcholine receptor protein alpha-7 subunit 81.68% 88.42%
CHEMBL2514 O95665 Neurotensin receptor 2 81.08% 100.00%
CHEMBL3776 Q14790 Caspase-8 80.68% 97.06%
CHEMBL2815 P04629 Nerve growth factor receptor Trk-A 80.36% 87.16%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 80.28% 96.21%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139583163
LOTUS LTS0083134
wikiData Q75055129