Mulin-11-ene-13-alpha-hydroxy-14-alpha-acetoxy-20-oic acid

Details

Top
Internal ID c5240241-31bf-4966-9b82-2242306d4859
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Valparane and mulinane diterpenoids
IUPAC Name (3R,3aS,5aS,7R,8S,10aS,10bS)-7-acetyloxy-8-hydroxy-5a,8-dimethyl-3-propan-2-yl-2,3,4,5,6,7,10a,10b-octahydro-1H-cyclohepta[g]indene-3a-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C22H34O5/c1-13(2)15-6-7-17-16-8-9-21(5,26)18(27-14(3)23)12-20(16,4)10-11-22(15,17)19(24)25/h8-9,13,15-18,26H,6-7,10-12H2,1-5H3,(H,24,25)/t15-,16+,17+,18-,20+,21+,22+/m1/s1
InChI Key JJIIOGRIIJVYAS-ZELOLHMESA-N
Popularity 2 references in papers

Physical and Chemical Properties

Top
Molecular Formula C22H34O5
Molecular Weight 378.50 g/mol
Exact Mass 378.24062418 g/mol
Topological Polar Surface Area (TPSA) 83.80 Ų
XlogP 3.90

Synonyms

Top
7-Carboxymethyl-8-hydroxy-3-isopropyl-5a,8-dimethyl-2,3,4,5,5a,6,7,8,10a,10b-decahydro-1H-cyclohepta[e]indene-3a-carboxylic acid
cyclohept[e]indene-3a(1H)-carboxylic acid, 7-(acetyloxy)-2,3,4,5,5a,6,7,8,10a,10b-decahydro-8-hydroxy-5a,8-dimethyl-3-(1-methylethyl)-, (3R,3aS,5aS,7R,8S,10aS,10bS)-
InChI=1/C22H34O5/c1-13(2)15-6-7-17-16-8-9-21(5,26)18(27-14(3)23)12-20(16,4)10-11-22(15,17)19(24)25/h8-9,13,15-18,26H,6-7,10-12H2,1-5H3,(H,24,25)/t15-,16+,17+,18-,20+,21+,22+/m1/s
rel-(3R,3aS,5aS,7R,8S,10aS,10bS)-7-(acetyloxy)-8-hydroxy-3-isopropyl-5a,8-dimethyl-2,3,4,5,5a,6,7,8,10a,10b-decahydrocyclohepta[e]indene-3a(1H)-carboxylic acid

2D Structure

Top
2D Structure of Mulin-11-ene-13-alpha-hydroxy-14-alpha-acetoxy-20-oic acid

3D Structure

Top

ADMET Properties (via admetSAR 2)

Top
Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

Top

Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 98.04% 94.45%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.78% 96.09%
CHEMBL4685 P14902 Indoleamine 2,3-dioxygenase 93.34% 96.38%
CHEMBL221 P23219 Cyclooxygenase-1 93.20% 90.17%
CHEMBL1966 Q02127 Dihydroorotate dehydrogenase 93.05% 96.09%
CHEMBL284 P27487 Dipeptidyl peptidase IV 92.39% 95.69%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 92.12% 91.11%
CHEMBL2179 P04062 Beta-glucocerebrosidase 89.60% 85.31%
CHEMBL340 P08684 Cytochrome P450 3A4 88.93% 91.19%
CHEMBL4227 P25090 Lipoxin A4 receptor 87.61% 100.00%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 87.60% 85.14%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 86.54% 99.23%
CHEMBL2007625 O75874 Isocitrate dehydrogenase [NADP] cytoplasmic 84.19% 99.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 83.89% 95.89%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.60% 91.07%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 82.94% 91.03%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.90% 97.14%
CHEMBL3359 P21462 Formyl peptide receptor 1 82.73% 93.56%
CHEMBL2413 P32246 C-C chemokine receptor type 1 82.05% 89.50%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 81.85% 95.56%
CHEMBL5608 Q16288 NT-3 growth factor receptor 81.82% 95.89%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 81.15% 93.03%
CHEMBL2111367 P27986 PI3-kinase p110-alpha/p85-alpha 81.02% 94.33%
CHEMBL253 P34972 Cannabinoid CB2 receptor 80.20% 97.25%

Plants that contains it

Top
Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Azorella prolifera

Cross-Links

Top
PubChem 637310
LOTUS LTS0085578
wikiData Q105129675