Monomethyl kolavate

Details

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Internal ID 6d455915-8ee3-42da-b410-21893fa3cafa
Taxonomy Lipids and lipid-like molecules > Prenol lipids > Diterpenoids > Colensane and clerodane diterpenoids
IUPAC Name (4aR,5S,6R,8aR)-5-[(E)-5-methoxy-3-methyl-5-oxopent-3-enyl]-5,6,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalene-1-carboxylic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C21H32O4/c1-14(13-18(22)25-5)9-11-20(3)15(2)10-12-21(4)16(19(23)24)7-6-8-17(20)21/h7,13,15,17H,6,8-12H2,1-5H3,(H,23,24)/b14-13+/t15-,17-,20+,21+/m1/s1
InChI Key CCDSRPQULZAXRF-LIECZFJOSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C21H32O4
Molecular Weight 348.50 g/mol
Exact Mass 348.23005950 g/mol
Topological Polar Surface Area (TPSA) 63.60 Ų
XlogP 5.80

Synonyms

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24513-41-5
(4aR,5S,6R,8aR)-5-[(E)-5-methoxy-3-methyl-5-oxopent-3-enyl]-5,6,8a-trimethyl-3,4,4a,6,7,8-hexahydronaphthalene-1-carboxylic acid
AKOS040762065
FS-9648
1-Naphthalenecarboxylic acid, 3,4,4a,5,6,7,8,8a-octahydro-5-[(3E)-5-methoxy-3-methyl-5-oxo-3-pentenyl]-5,6,8a-trimethyl-, (4aR,5S,6R,8aR)- (9CI); 17,19-Dinor-8H-labda-3,13-diene-15,18-dioic acid, 5,9-dimethyl-, 15-methyl ester, (-)- (8CI)

2D Structure

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2D Structure of Monomethyl kolavate

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL4040 P28482 MAP kinase ERK2 98.95% 83.82%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.83% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 97.25% 96.09%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.23% 94.45%
CHEMBL2581 P07339 Cathepsin D 87.76% 98.95%
CHEMBL340 P08684 Cytochrome P450 3A4 85.10% 91.19%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.94% 97.09%
CHEMBL4227 P25090 Lipoxin A4 receptor 82.84% 100.00%
CHEMBL5028 O14672 ADAM10 82.59% 97.50%
CHEMBL1293249 Q13887 Kruppel-like factor 5 82.37% 86.33%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 82.00% 93.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 81.99% 97.25%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 80.92% 95.56%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 80.18% 95.50%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 11462192
LOTUS LTS0057721
wikiData Q104953177