Monacyclinone B

Details

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Internal ID 0262fe00-b145-40c2-a2e9-01daa26fe539
Taxonomy Phenylpropanoids and polyketides > Angucyclines
IUPAC Name 9-[(2R,5S,6S)-5-(dimethylamino)-6-methyloxan-2-yl]-1,5,8-trihydroxy-3-methylbenzo[a]anthracene-7,12-dione
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C27H27NO6/c1-12-9-16-19(29)11-17-23(22(16)20(30)10-12)26(32)15-6-5-14(25(31)24(15)27(17)33)21-8-7-18(28(3)4)13(2)34-21/h5-6,9-11,13,18,21,29-31H,7-8H2,1-4H3/t13-,18-,21+/m0/s1
InChI Key LCNXLRHNCJLJRN-LTBCBRHQSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C27H27NO6
Molecular Weight 461.50 g/mol
Exact Mass 461.18383758 g/mol
Topological Polar Surface Area (TPSA) 107.00 Ų
XlogP 4.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Monacyclinone B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.45% 91.11%
CHEMBL2581 P07339 Cathepsin D 98.96% 98.95%
CHEMBL1951 P21397 Monoamine oxidase A 98.54% 91.49%
CHEMBL1806 P11388 DNA topoisomerase II alpha 98.42% 89.00%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 95.59% 96.21%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.18% 95.56%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 93.43% 99.23%
CHEMBL5608 Q16288 NT-3 growth factor receptor 91.50% 95.89%
CHEMBL2345 P51812 Ribosomal protein S6 kinase alpha 3 90.54% 95.64%
CHEMBL1994 P08235 Mineralocorticoid receptor 88.44% 100.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 87.43% 96.09%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 87.42% 90.71%
CHEMBL3401 O75469 Pregnane X receptor 86.65% 94.73%
CHEMBL2378 P30307 Dual specificity phosphatase Cdc25C 86.29% 96.67%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 84.51% 94.00%
CHEMBL2094127 P06493 Cyclin-dependent kinase 1/cyclin B 84.03% 96.00%
CHEMBL340 P08684 Cytochrome P450 3A4 83.29% 91.19%
CHEMBL3137262 O60341 LSD1/CoREST complex 83.26% 97.09%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.00% 93.03%
CHEMBL241 Q14432 Phosphodiesterase 3A 82.11% 92.94%
CHEMBL4530 P00488 Coagulation factor XIII 82.08% 96.00%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139587334
LOTUS LTS0099087
wikiData Q77563540