Minutissamide I

Details

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Internal ID 5a010b5e-59f7-4bcf-ac33-5faad2981e9b
Taxonomy Phenylpropanoids and polyketides > Macrolactams
IUPAC Name 3-[(3S,6S,12S,15S,18S,21E,24S,27R,28R,31S)-3-(2-amino-2-oxoethyl)-21-ethylidene-27-hydroxy-15,18-bis[(1R)-1-hydroxyethyl]-6-[(1R)-1-methoxyethyl]-4-methyl-2,5,8,11,14,17,20,23,26,30-decaoxo-28-[(2S)-13-oxohexadecan-2-yl]-24-propan-2-yl-1,4,7,10,13,16,19,22,25,29-decazabicyclo[29.3.0]tetratriacontan-12-yl]propanamide
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C58H98N12O17/c1-11-22-36(73)24-20-18-16-14-13-15-17-19-23-32(5)45-49(77)56(84)65-44(31(3)4)53(81)62-37(12-2)51(79)67-47(34(7)72)55(83)68-46(33(6)71)54(82)63-38(26-27-41(59)74)50(78)61-30-43(76)64-48(35(8)87-10)58(86)69(9)40(29-42(60)75)57(85)70-28-21-25-39(70)52(80)66-45/h12,31-35,38-40,44-49,71-72,77H,11,13-30H2,1-10H3,(H2,59,74)(H2,60,75)(H,61,78)(H,62,81)(H,63,82)(H,64,76)(H,65,84)(H,66,80)(H,67,79)(H,68,83)/b37-12+/t32-,33+,34+,35+,38-,39-,40-,44-,45+,46-,47-,48-,49+/m0/s1
InChI Key AMMOFLIZXVOQED-SQXQCVBBSA-N
Popularity 4 references in papers

Physical and Chemical Properties

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Molecular Formula C58H98N12O17
Molecular Weight 1235.50 g/mol
Exact Mass 1234.71728970 g/mol
Topological Polar Surface Area (TPSA) 447.00 Ų
XlogP 0.90

Synonyms

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(-)-Minutissamide I
CHEMBL2148020

2D Structure

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2D Structure of Minutissamide I

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 99.78% 96.09%
CHEMBL2581 P07339 Cathepsin D 99.58% 98.95%
CHEMBL325 Q13547 Histone deacetylase 1 99.01% 95.92%
CHEMBL4588 P22894 Matrix metalloproteinase 8 98.57% 94.66%
CHEMBL1937 Q92769 Histone deacetylase 2 98.42% 94.75%
CHEMBL4040 P28482 MAP kinase ERK2 98.22% 83.82%
CHEMBL5103 Q969S8 Histone deacetylase 10 98.19% 90.08%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 97.90% 94.45%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 97.84% 82.38%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.57% 91.11%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 96.55% 93.00%
CHEMBL5608 Q16288 NT-3 growth factor receptor 96.06% 95.89%
CHEMBL3837 P07711 Cathepsin L 95.84% 96.61%
CHEMBL2443 P49862 Kallikrein 7 95.55% 94.00%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 95.20% 95.50%
CHEMBL4071 P08311 Cathepsin G 95.06% 94.64%
CHEMBL3524 P56524 Histone deacetylase 4 94.80% 92.97%
CHEMBL221 P23219 Cyclooxygenase-1 94.55% 90.17%
CHEMBL333 P08253 Matrix metalloproteinase-2 94.18% 96.31%
CHEMBL1902 P62942 FK506-binding protein 1A 93.47% 97.05%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 92.35% 100.00%
CHEMBL5469 Q14289 Protein tyrosine kinase 2 beta 92.19% 91.03%
CHEMBL3392948 Q9NP59 Solute carrier family 40 member 1 92.14% 95.00%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.07% 97.25%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 91.84% 85.14%
CHEMBL3137262 O60341 LSD1/CoREST complex 91.02% 97.09%
CHEMBL255 P29275 Adenosine A2b receptor 89.84% 98.59%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 89.53% 90.71%
CHEMBL344 Q99705 Melanin-concentrating hormone receptor 1 89.24% 92.50%
CHEMBL321 P14780 Matrix metalloproteinase 9 88.98% 92.12%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 88.82% 95.56%
CHEMBL226 P30542 Adenosine A1 receptor 88.68% 95.93%
CHEMBL213 P08588 Beta-1 adrenergic receptor 88.27% 95.56%
CHEMBL4227 P25090 Lipoxin A4 receptor 87.83% 100.00%
CHEMBL3310 Q96DB2 Histone deacetylase 11 87.47% 88.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 87.40% 89.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 87.08% 97.64%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 87.00% 93.03%
CHEMBL228 P31645 Serotonin transporter 86.88% 95.51%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 86.72% 91.81%
CHEMBL3060 Q9Y345 Glycine transporter 2 86.19% 99.17%
CHEMBL3130 O00329 PI3-kinase p110-delta subunit 86.13% 96.47%
CHEMBL1871 P10275 Androgen Receptor 85.05% 96.43%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 85.03% 96.90%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 84.94% 99.23%
CHEMBL332 P03956 Matrix metalloproteinase-1 84.81% 94.50%
CHEMBL2096618 P11274 Bcr/Abl fusion protein 84.31% 85.83%
CHEMBL3359 P21462 Formyl peptide receptor 1 83.52% 93.56%
CHEMBL5203 P33316 dUTP pyrophosphatase 83.26% 99.18%
CHEMBL4026 P40763 Signal transducer and activator of transcription 3 83.04% 82.69%
CHEMBL3430907 Q96GD4 Aurora kinase B/Inner centromere protein 82.75% 97.50%
CHEMBL2413 P32246 C-C chemokine receptor type 1 81.78% 89.50%
CHEMBL299 P17252 Protein kinase C alpha 81.78% 98.03%
CHEMBL4005 P42336 PI3-kinase p110-alpha subunit 81.76% 97.47%
CHEMBL3892 Q99500 Sphingosine 1-phosphate receptor Edg-3 80.57% 97.29%
CHEMBL241 Q14432 Phosphodiesterase 3A 80.56% 92.94%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 71460174
LOTUS LTS0100420
wikiData Q105096387