Milbemycin beta14

Details

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Internal ID 78234736-f7d5-45c5-a6bc-0fa156c151ad
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues > Milbemycins
IUPAC Name (1S,5'S,6'R,10E,12Z,14R,16Z,19R,21R)-6'-ethyl-7-hydroxy-10-(hydroxymethyl)-5',6,14,16-tetramethylspiro[2,20-dioxatricyclo[17.3.1.04,9]tricosa-4(9),5,7,10,12,16-hexaene-21,2'-oxane]-3-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H44O6/c1-6-30-22(4)12-13-32(38-30)18-26-16-25(37-32)11-10-21(3)14-20(2)8-7-9-24(19-33)27-17-29(34)23(5)15-28(27)31(35)36-26/h7-10,15,17,20,22,25-26,30,33-34H,6,11-14,16,18-19H2,1-5H3/b8-7-,21-10-,24-9-/t20-,22-,25+,26-,30+,32+/m0/s1
InChI Key CYJZPVCNDSUHMR-GAPVIADPSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C32H44O6
Molecular Weight 524.70 g/mol
Exact Mass 524.31378912 g/mol
Topological Polar Surface Area (TPSA) 85.20 Ų
XlogP 6.20

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Milbemycin beta14

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.02% 91.11%
CHEMBL218 P21554 Cannabinoid CB1 receptor 95.84% 96.61%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.26% 95.56%
CHEMBL253 P34972 Cannabinoid CB2 receptor 94.82% 97.25%
CHEMBL2581 P07339 Cathepsin D 92.76% 98.95%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 92.10% 96.09%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 92.07% 94.80%
CHEMBL1293249 Q13887 Kruppel-like factor 5 91.43% 86.33%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.35% 97.09%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 89.33% 96.95%
CHEMBL1806 P11388 DNA topoisomerase II alpha 88.48% 89.00%
CHEMBL3401 O75469 Pregnane X receptor 86.97% 94.73%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 85.25% 99.23%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 83.59% 94.00%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 83.15% 91.07%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.02% 93.03%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 82.72% 97.14%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 81.63% 97.33%
CHEMBL1937 Q92769 Histone deacetylase 2 81.57% 94.75%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.48% 100.00%
CHEMBL4803 P29474 Nitric-oxide synthase, endothelial 81.15% 86.00%
CHEMBL2781 P19634 Sodium/hydrogen exchanger 1 81.09% 90.24%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 80.89% 92.62%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139585002
LOTUS LTS0084799
wikiData Q77380490