Milbemycin alpha31

Details

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Internal ID c70548c4-3db3-4099-9977-8ab55b24dc2c
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (4S,5'S,6R,6'R,8R,10Z,13R,14Z,16E)-6'-ethyl-21-hydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-1(24),10,14,16,20,22-hexaene-6,2'-oxane]-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C32H42O6/c1-6-27-21(4)12-13-32(38-27)17-25-16-24(37-32)11-10-20(3)14-19(2)8-7-9-23-18-35-30-28(23)26(31(34)36-25)15-22(5)29(30)33/h7-10,15,19,21,24-25,27,33H,6,11-14,16-18H2,1-5H3/b8-7-,20-10-,23-9-/t19-,21-,24+,25-,27+,32+/m0/s1
InChI Key ZYUWEJDCQXCSMF-SSKSLTGKSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C32H42O6
Molecular Weight 522.70 g/mol
Exact Mass 522.29813906 g/mol
Topological Polar Surface Area (TPSA) 74.20 Ų
XlogP 6.70

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Milbemycin alpha31

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 99.36% 91.11%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 94.58% 95.56%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 93.20% 96.21%
CHEMBL1293249 Q13887 Kruppel-like factor 5 93.19% 86.33%
CHEMBL4481 P35228 Nitric oxide synthase, inducible 92.85% 94.80%
CHEMBL2581 P07339 Cathepsin D 92.20% 98.95%
CHEMBL1806 P11388 DNA topoisomerase II alpha 92.00% 89.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 91.82% 96.09%
CHEMBL3401 O75469 Pregnane X receptor 90.69% 94.73%
CHEMBL3137262 O60341 LSD1/CoREST complex 90.06% 97.09%
CHEMBL218 P21554 Cannabinoid CB1 receptor 89.77% 96.61%
CHEMBL253 P34972 Cannabinoid CB2 receptor 89.23% 97.25%
CHEMBL4793 Q86TI2 Dipeptidyl peptidase IX 87.91% 96.95%
CHEMBL3713062 P10646 Tissue factor pathway inhibitor 86.06% 97.33%
CHEMBL1994 P08235 Mineralocorticoid receptor 85.76% 100.00%
CHEMBL4530 P00488 Coagulation factor XIII 85.28% 96.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 83.56% 99.23%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 82.13% 94.00%
CHEMBL5966 P55899 IgG receptor FcRn large subunit p51 81.63% 90.93%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 81.42% 82.38%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 81.12% 92.62%
CHEMBL5608 Q16288 NT-3 growth factor receptor 80.41% 95.89%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 80.25% 93.03%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139585354
LOTUS LTS0212418
wikiData Q77420734