micropeptin 88-C

Details

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Internal ID fabf5d92-3e35-409f-9d8e-64c3f2e16b0c
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name 5-[[(2S,5S,8S,11R,12S,15S,21R)-5-benzyl-8-[(2S)-butan-2-yl]-21-hydroxy-15-[(4-hydroxyphenyl)methyl]-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-2-[[(2S)-2-(butanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoic acid
SMILES (Canonical) CCCC(=O)NC(CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)NC2C(OC(=O)C(NC(=O)C(N(C(=O)C(N3C(CCC(C3=O)NC(=O)C(NC2=O)CC4=CC=C(C=C4)O)O)C(C)C)C)CC5=CC=CC=C5)C(C)CC)C)C(=O)O
SMILES (Isomeric) CCCC(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)NC(CCC(=O)N[C@H]2[C@H](OC(=O)[C@@H](NC(=O)[C@@H](N(C(=O)[C@@H](N3[C@@H](CCC(C3=O)NC(=O)[C@@H](NC2=O)CC4=CC=C(C=C4)O)O)C(C)C)C)CC5=CC=CC=C5)[C@@H](C)CC)C)C(=O)O
InChI InChI=1S/C57H76N8O15/c1-8-13-44(68)58-41(28-35-16-20-37(66)21-17-35)50(71)60-40(56(77)78)24-26-45(69)62-48-33(6)80-57(79)47(32(5)9-2)63-52(73)43(30-34-14-11-10-12-15-34)64(7)55(76)49(31(3)4)65-46(70)27-25-39(54(65)75)59-51(72)42(61-53(48)74)29-36-18-22-38(67)23-19-36/h10-12,14-23,31-33,39-43,46-49,66-67,70H,8-9,13,24-30H2,1-7H3,(H,58,68)(H,59,72)(H,60,71)(H,61,74)(H,62,69)(H,63,73)(H,77,78)/t32-,33+,39?,40?,41-,42-,43-,46+,47-,48-,49-/m0/s1
InChI Key QVFJAFKXTMGGJM-QNCKKECNSA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C57H76N8O15
Molecular Weight 1113.30 g/mol
Exact Mass 1112.54301375 g/mol
Topological Polar Surface Area (TPSA) 340.00 Ų
XlogP 4.60

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of micropeptin 88-C

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.97% 98.95%
CHEMBL3837 P07711 Cathepsin L 99.48% 96.61%
CHEMBL4072 P07858 Cathepsin B 98.29% 93.67%
CHEMBL3060 Q9Y345 Glycine transporter 2 97.51% 99.17%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 96.74% 93.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 95.89% 97.64%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 95.68% 96.09%
CHEMBL4040 P28482 MAP kinase ERK2 95.53% 83.82%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.23% 95.56%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 94.18% 97.14%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 93.85% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.84% 94.45%
CHEMBL5103 Q969S8 Histone deacetylase 10 92.99% 90.08%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 92.46% 95.89%
CHEMBL3359 P21462 Formyl peptide receptor 1 92.13% 93.56%
CHEMBL1806 P11388 DNA topoisomerase II alpha 91.53% 89.00%
CHEMBL226 P30542 Adenosine A1 receptor 91.26% 95.93%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 89.54% 82.38%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 89.19% 99.23%
CHEMBL333 P08253 Matrix metalloproteinase-2 88.96% 96.31%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 88.34% 92.67%
CHEMBL236 P41143 Delta opioid receptor 88.15% 99.35%
CHEMBL221 P23219 Cyclooxygenase-1 88.08% 90.17%
CHEMBL340 P08684 Cytochrome P450 3A4 86.10% 91.19%
CHEMBL3137262 O60341 LSD1/CoREST complex 86.02% 97.09%
CHEMBL2413 P32246 C-C chemokine receptor type 1 85.96% 89.50%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 85.49% 100.00%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 85.16% 90.71%
CHEMBL5608 Q16288 NT-3 growth factor receptor 84.77% 95.89%
CHEMBL1949 P62937 Cyclophilin A 83.74% 98.57%
CHEMBL255 P29275 Adenosine A2b receptor 83.28% 98.59%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.25% 93.03%
CHEMBL2535 P11166 Glucose transporter 83.08% 98.75%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 82.95% 97.23%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 81.57% 92.08%
CHEMBL259 P32245 Melanocortin receptor 4 80.80% 95.38%
CHEMBL2288 Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 80.38% 91.71%
CHEMBL4393 P39900 Matrix metalloproteinase 12 80.28% 92.22%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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Cross-Links

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PubChem 139586907
LOTUS LTS0223160
wikiData Q77517301