Micropeptin 88 B

Details

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Internal ID abe7c035-a362-4533-bd75-7cc26cc9688c
Taxonomy Organic acids and derivatives > Peptidomimetics > Depsipeptides > Cyclic depsipeptides
IUPAC Name (2S)-5-[[(2S,5S,8S,11R,12S,15S,18S,21R)-5-benzyl-8-[(2S)-butan-2-yl]-15-(2-carboxyethyl)-21-hydroxy-4,11-dimethyl-3,6,9,13,16,22-hexaoxo-2-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]amino]-2-[[(2S)-2-(butanoylamino)-3-(4-hydroxyphenyl)propanoyl]amino]-5-oxopentanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C53H74N8O16/c1-8-13-39(63)54-37(26-32-16-18-33(62)19-17-32)47(69)57-36(52(74)75)20-23-40(64)58-44-30(6)77-53(76)43(29(5)9-2)59-48(70)38(27-31-14-11-10-12-15-31)60(7)51(73)45(28(3)4)61-41(65)24-21-35(50(61)72)56-46(68)34(55-49(44)71)22-25-42(66)67/h10-12,14-19,28-30,34-38,41,43-45,62,65H,8-9,13,20-27H2,1-7H3,(H,54,63)(H,55,71)(H,56,68)(H,57,69)(H,58,64)(H,59,70)(H,66,67)(H,74,75)/t29-,30+,34-,35-,36-,37-,38-,41+,43-,44-,45-/m0/s1
InChI Key YCVYNQFZZBCUTC-NPYWRNGISA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C53H74N8O16
Molecular Weight 1079.20 g/mol
Exact Mass 1078.52227830 g/mol
Topological Polar Surface Area (TPSA) 357.00 Ų
XlogP 2.80

Synonyms

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CHEMBL538538

2D Structure

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2D Structure of Micropeptin 88 B

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.98% 98.95%
CHEMBL3837 P07711 Cathepsin L 99.57% 96.61%
CHEMBL3060 Q9Y345 Glycine transporter 2 98.28% 99.17%
CHEMBL4040 P28482 MAP kinase ERK2 97.68% 83.82%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 96.96% 93.00%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 96.40% 96.09%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 95.62% 97.64%
CHEMBL4072 P07858 Cathepsin B 95.49% 93.67%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 95.15% 95.56%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 94.94% 97.14%
CHEMBL236 P41143 Delta opioid receptor 94.59% 99.35%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 94.56% 91.11%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 94.55% 94.45%
CHEMBL5103 Q969S8 Histone deacetylase 10 94.12% 90.08%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 93.48% 95.89%
CHEMBL3359 P21462 Formyl peptide receptor 1 92.32% 93.56%
CHEMBL2069156 Q14145 Kelch-like ECH-associated protein 1 92.05% 82.38%
CHEMBL226 P30542 Adenosine A1 receptor 92.01% 95.93%
CHEMBL221 P23219 Cyclooxygenase-1 91.43% 90.17%
CHEMBL1806 P11388 DNA topoisomerase II alpha 90.97% 89.00%
CHEMBL3038477 P67870 Casein kinase II alpha/beta 90.01% 99.23%
CHEMBL2095172 P14867 GABA-A receptor; alpha-1/beta-2/gamma-2 88.31% 92.67%
CHEMBL340 P08684 Cytochrome P450 3A4 87.91% 91.19%
CHEMBL2413 P32246 C-C chemokine receptor type 1 86.74% 89.50%
CHEMBL255 P29275 Adenosine A2b receptor 86.40% 98.59%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 86.36% 90.71%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 85.97% 85.14%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.61% 95.89%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 85.56% 93.10%
CHEMBL259 P32245 Melanocortin receptor 4 85.41% 95.38%
CHEMBL3137262 O60341 LSD1/CoREST complex 84.88% 97.09%
CHEMBL2000 P03952 Plasma kallikrein 84.53% 93.92%
CHEMBL5939 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 84.48% 100.00%
CHEMBL1907600 Q00535 Cyclin-dependent kinase 5/CDK5 activator 1 83.54% 93.03%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 83.23% 97.23%
CHEMBL1949 P62937 Cyclophilin A 82.88% 98.57%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 82.13% 98.33%
CHEMBL1860 P10827 Thyroid hormone receptor alpha 81.79% 99.15%
CHEMBL4769 O95749 Geranylgeranyl pyrophosphate synthetase 81.57% 92.08%
CHEMBL5163 Q9NY46 Sodium channel protein type III alpha subunit 81.56% 96.90%
CHEMBL333 P08253 Matrix metalloproteinase-2 81.33% 96.31%
CHEMBL1255126 O15151 Protein Mdm4 80.71% 90.20%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 10629964
LOTUS LTS0133039
wikiData Q105346540