Microginin 765

Details

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Internal ID 7a009b1d-18aa-4b3f-83ff-75499df6e0bf
Taxonomy Organic acids and derivatives > Peptidomimetics > Hybrid peptides
IUPAC Name 2-[[2-[[1-[2-[(3-amino-10,10-dichloro-2-hydroxydecanoyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C36H49Cl2N5O9/c1-21(40-34(49)31(46)26(39)7-4-2-3-5-9-30(37)38)35(50)43-18-6-8-29(43)33(48)41-27(19-22-10-14-24(44)15-11-22)32(47)42-28(36(51)52)20-23-12-16-25(45)17-13-23/h10-17,21,26-31,44-46H,2-9,18-20,39H2,1H3,(H,40,49)(H,41,48)(H,42,47)(H,51,52)
InChI Key RUVSWVJIBKXISF-UHFFFAOYSA-N
Popularity 3 references in papers

Physical and Chemical Properties

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Molecular Formula C36H49Cl2N5O9
Molecular Weight 766.70 g/mol
Exact Mass 765.2907335 g/mol
Topological Polar Surface Area (TPSA) 232.00 Ų
XlogP 1.60

Synonyms

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DTXSID501334047

2D Structure

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2D Structure of Microginin 765

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL2581 P07339 Cathepsin D 99.68% 98.95%
CHEMBL3837 P07711 Cathepsin L 98.78% 96.61%
CHEMBL4040 P28482 MAP kinase ERK2 98.61% 83.82%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 98.61% 96.09%
CHEMBL2514 O95665 Neurotensin receptor 2 98.21% 100.00%
CHEMBL2107 P61073 C-X-C chemokine receptor type 4 98.04% 93.10%
CHEMBL1795139 Q8IU80 Transmembrane protease serine 6 97.06% 98.33%
CHEMBL230 P35354 Cyclooxygenase-2 96.81% 89.63%
CHEMBL4123 P30989 Neurotensin receptor 1 96.16% 96.67%
CHEMBL3359 P21462 Formyl peptide receptor 1 95.92% 93.56%
CHEMBL5845 P23415 Glycine receptor subunit alpha-1 94.88% 90.71%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 93.01% 94.45%
CHEMBL1907591 P30926 Neuronal acetylcholine receptor; alpha4/beta4 92.84% 100.00%
CHEMBL4979 P13866 Sodium/glucose cotransporter 1 92.64% 98.24%
CHEMBL1255126 O15151 Protein Mdm4 92.18% 90.20%
CHEMBL5608 Q16288 NT-3 growth factor receptor 92.17% 95.89%
CHEMBL4227 P25090 Lipoxin A4 receptor 91.82% 100.00%
CHEMBL1907594 P30926 Neuronal acetylcholine receptor; alpha3/beta4 91.47% 97.23%
CHEMBL3060 Q9Y345 Glycine transporter 2 91.33% 99.17%
CHEMBL340 P08684 Cytochrome P450 3A4 90.56% 91.19%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.52% 95.56%
CHEMBL4777 P25929 Neuropeptide Y receptor type 1 90.41% 96.67%
CHEMBL221 P23219 Cyclooxygenase-1 90.37% 90.17%
CHEMBL249 P25103 Neurokinin 1 receptor 90.19% 99.17%
CHEMBL3137262 O60341 LSD1/CoREST complex 89.70% 97.09%
CHEMBL4361 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 88.95% 95.52%
CHEMBL237 P41145 Kappa opioid receptor 88.82% 98.10%
CHEMBL4394 Q9NYA1 Sphingosine kinase 1 88.65% 96.03%
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 88.19% 91.11%
CHEMBL3976 Q9UHL4 Dipeptidyl peptidase II 87.30% 92.29%
CHEMBL2274 Q9H228 Sphingosine 1-phosphate receptor Edg-8 87.02% 100.00%
CHEMBL1907603 Q05586 Glutamate NMDA receptor; GRIN1/GRIN2B 86.74% 95.89%
CHEMBL3807 P17706 T-cell protein-tyrosine phosphatase 86.73% 93.00%
CHEMBL5852 Q96P65 Pyroglutamylated RFamide peptide receptor 86.21% 85.00%
CHEMBL2693 Q9UIQ6 Cystinyl aminopeptidase 85.84% 97.64%
CHEMBL236 P41143 Delta opioid receptor 85.78% 99.35%
CHEMBL4478 Q00975 Voltage-gated N-type calcium channel alpha-1B subunit 85.61% 97.14%
CHEMBL233 P35372 Mu opioid receptor 82.94% 97.93%
CHEMBL4187 Q99250 Sodium channel protein type II alpha subunit 82.25% 95.50%
CHEMBL5043 Q6P179 Endoplasmic reticulum aminopeptidase 2 82.20% 91.81%
CHEMBL1873 P00750 Tissue-type plasminogen activator 82.18% 93.33%
CHEMBL5103 Q969S8 Histone deacetylase 10 82.10% 90.08%
CHEMBL335 P18031 Protein-tyrosine phosphatase 1B 81.50% 95.17%
CHEMBL1907599 P05556 Integrin alpha-4/beta-1 81.13% 92.86%
CHEMBL3192 Q9BY41 Histone deacetylase 8 80.90% 93.99%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 146684938
LOTUS LTS0082466
wikiData Q104246249