Methylgraviphane

Details

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Internal ID 2e500fea-6e90-4e40-ace3-e89c658e7fc5
Taxonomy Benzenoids > Phenol ethers > Anisoles
IUPAC Name 3-methoxytricyclo[20.2.2.02,7]hexacosa-1(24),2(7),3,5,22,25-hexaene-5,24,25-triol
SMILES (Canonical) COC1=CC(=CC2=C1C3=C(C=C(CCCCCCCCCCCCCC2)C=C3O)O)O
SMILES (Isomeric) COC1=CC(=CC2=C1C3=C(C=C(CCCCCCCCCCCCCC2)C=C3O)O)O
InChI InChI=1S/C27H38O4/c1-31-25-19-22(28)18-21-15-13-11-9-7-5-3-2-4-6-8-10-12-14-20-16-23(29)27(26(21)25)24(30)17-20/h16-19,28-30H,2-15H2,1H3
InChI Key VHTRJVITHPENFV-UHFFFAOYSA-N
Popularity 2 references in papers

Physical and Chemical Properties

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Molecular Formula C27H38O4
Molecular Weight 426.60 g/mol
Exact Mass 426.27700969 g/mol
Topological Polar Surface Area (TPSA) 69.90 Ų
XlogP 9.20

Synonyms

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3-methoxytricyclo(20.2.2.02,7)hexacosa-1(24),2(7),3,5,22,25-hexaene-5,24,25-triol
3-methoxytricyclo[20.2.2.02,7]hexacosa-1(24),2(7),3,5,22,25-hexaene-5,24,25-triol
RefChem:158226
26002-04-0
CHEMBL375783

2D Structure

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2D Structure of Methylgraviphane

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.44% 91.11%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 94.21% 96.09%
CHEMBL2581 P07339 Cathepsin D 90.88% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 90.12% 95.56%
CHEMBL4208 P20618 Proteasome component C5 90.03% 90.00%
CHEMBL1951 P21397 Monoamine oxidase A 89.67% 91.49%
CHEMBL4203 Q9HAZ1 Dual specificity protein kinase CLK4 88.79% 94.45%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.68% 86.33%
CHEMBL2635 P51452 Dual specificity protein phosphatase 3 85.86% 94.00%
CHEMBL2535 P11166 Glucose transporter 85.17% 98.75%
CHEMBL5608 Q16288 NT-3 growth factor receptor 85.09% 95.89%
CHEMBL241 Q14432 Phosphodiesterase 3A 84.94% 92.94%
CHEMBL3192 Q9BY41 Histone deacetylase 8 84.73% 93.99%
CHEMBL4630 O14757 Serine/threonine-protein kinase Chk1 84.12% 97.03%
CHEMBL2041 P07949 Tyrosine-protein kinase receptor RET 82.76% 91.79%
CHEMBL3060 Q9Y345 Glycine transporter 2 82.03% 99.17%
CHEMBL4306 P22460 Voltage-gated potassium channel subunit Kv1.5 82.01% 94.03%
CHEMBL2373 P21730 C5a anaphylatoxin chemotactic receptor 81.40% 92.62%
CHEMBL5311 P37023 Serine/threonine-protein kinase receptor R3 81.32% 82.67%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
To see more specific details click the taxa you are interested in.
Grevillea robusta

Cross-Links

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PubChem 44419741
NPASS NPC82299
ChEMBL CHEMBL375783
LOTUS LTS0164906
wikiData Q104401573