Methoxy-macrolactin 1

Details

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Internal ID 4efff879-7656-4164-84c0-62c8728c4bf4
Taxonomy Phenylpropanoids and polyketides > Macrolides and analogues
IUPAC Name (3Z,5E,8S,11Z,14S,16R,17E,19E,24R)-14-hydroxy-16-methoxy-24-methyl-8-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1-oxacyclotetracosa-3,5,9,11,17,19-hexaen-2-one
SMILES (Canonical)
SMILES (Isomeric)
InChI InChI=1S/C31H46O10/c1-22-14-8-4-3-5-10-18-25(38-2)20-23(33)15-9-6-11-16-24(17-12-7-13-19-27(34)39-22)40-31-30(37)29(36)28(35)26(21-32)41-31/h3,5-7,9-13,16,18-19,22-26,28-33,35-37H,4,8,14-15,17,20-21H2,1-2H3/b5-3+,9-6-,12-7+,16-11?,18-10+,19-13-/t22-,23+,24-,25+,26-,28-,29+,30-,31-/m1/s1
InChI Key RQTSCDVSKIOZMR-RCJUSREISA-N
Popularity 0 references in papers

Physical and Chemical Properties

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Molecular Formula C31H46O10
Molecular Weight 578.70 g/mol
Exact Mass 578.30909766 g/mol
Topological Polar Surface Area (TPSA) 155.00 Ų
XlogP 3.40

Synonyms

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There are no found synonyms.

2D Structure

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2D Structure of Methoxy-macrolactin 1

3D Structure

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ADMET Properties (via admetSAR 2)

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Target Value Probability (raw) Probability (%)
No predicted properties yet!

Targets

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Proven Targets:

CHEMBL ID UniProt ID Name Min activity Assay type Source
No proven targets yet!

Predicted Targets (via Super-PRED):

CHEMBL ID UniProt ID Name Probability Model accuracy
CHEMBL5619 P27695 DNA-(apurinic or apyrimidinic site) lyase 97.79% 91.11%
CHEMBL3137262 O60341 LSD1/CoREST complex 94.64% 97.09%
CHEMBL253 P34972 Cannabinoid CB2 receptor 92.79% 97.25%
CHEMBL2581 P07339 Cathepsin D 92.70% 98.95%
CHEMBL3108638 O15164 Transcription intermediary factor 1-alpha 92.40% 95.56%
CHEMBL2007 P16234 Platelet-derived growth factor receptor alpha 88.86% 91.07%
CHEMBL3251 P19838 Nuclear factor NF-kappa-B p105 subunit 88.06% 96.09%
CHEMBL5608 Q16288 NT-3 growth factor receptor 87.13% 95.89%
CHEMBL1293249 Q13887 Kruppel-like factor 5 86.43% 86.33%
CHEMBL3880 P07900 Heat shock protein HSP 90-alpha 85.64% 96.21%
CHEMBL4261 Q16665 Hypoxia-inducible factor 1 alpha 84.74% 85.14%
CHEMBL5255 O00206 Toll-like receptor 4 83.64% 92.50%
CHEMBL4016 P42262 Glutamate receptor ionotropic, AMPA 2 81.49% 86.92%
CHEMBL1994 P08235 Mineralocorticoid receptor 81.34% 100.00%
CHEMBL3060 Q9Y345 Glycine transporter 2 80.84% 99.17%
CHEMBL3476 O15111 Inhibitor of nuclear factor kappa B kinase alpha subunit 80.37% 95.83%

Plants that contains it

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Below are displayed all the plants proven (via scientific papers) to contain this compound!
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There are no matching plants.

Cross-Links

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PubChem 139585470
LOTUS LTS0092549
wikiData Q77423184